The Cancer Biology Training Program (the Program) at The University of Michigan, currently in its twentieth year, is an interdisciplinary program whose central goal is to train exceptional junior investigators to address fundamental biological problems related to human cancer. The Program draws its strength from: the participation of 40 faculty members from 14 basic science and clinical departments within The University of Michigan;its association with The University of Michigan Comprehensive Cancer Center;and its involvement with the Program in Biomedical Sciences, through which graduate students are recruited to the Program. The Program trains both predoctoral and postdoctoral scholars with research opportunities focusing on a wide choice of topics in the field of cancer biology. In addition, it provides these trainees with didactic coursework and other programmatic activities that expose them to the depth and breadth of cancer research. Postdoctoral fellows will have completed a Ph.D. degree in one of the physical or biological sciences, or have completed an M.D. degree. Predoctoral students will comprise a subset of students accepted into the recently-approved Doctoral Program in Cancer Biology. All trainees have a significant interest in pursuing a career in some aspect of cancer-related research. Predoctoral trainees will be expected to graduate to outstanding postdoctoral positions, while postdoctoral trainees should assume leading academic and research positions.

Public Health Relevance

Cancer is one of the leading causes of illness and death in the United States. Determining the causes of cancer and discovery of new therapeutic approaches is required to improve the outcomes of cancer patients. The purpose of this grant is to train the next generation of cancer researchers, allowing them to make strides in the future as we continue to battle this disease.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA009676-22
Application #
8693928
Study Section
Subcommittee B - Comprehensiveness (NCI)
Program Officer
Damico, Mark W
Project Start
1997-09-30
Project End
2018-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
22
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Haase, Santiago; Garcia-Fabiani, María Belén; Carney, Stephen et al. (2018) Mutant ATRX: uncovering a new therapeutic target for glioma. Expert Opin Ther Targets 22:599-613
Morgan, Meredith A; Canman, Christine E (2018) Replication Stress: An Achilles' Heel of Glioma Cancer Stem-like Cells. Cancer Res 78:6713-6716
Thomas, Tina T; Chukkapalli, Sahiti; Van Noord, Raelene A et al. (2018) Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts. J Vis Exp :
Rosselli-Murai, Luciana K; Yates, Joel A; Yoshida, Sei et al. (2018) Loss of PTEN promotes formation of signaling-capable clathrin-coated pits. J Cell Sci 131:
Pinatti, L M; Walline, H M; Carey, T E (2018) Human Papillomavirus Genome Integration and Head and Neck Cancer. J Dent Res 97:691-700
Halbrook, Christopher J; Pasca di Magliano, Marina; Lyssiotis, Costas A (2018) Tumor cross-talk networks promote growth and support immune evasion in pancreatic cancer. Am J Physiol Gastrointest Liver Physiol 315:G27-G35
Schofield, Heather K; Zeller, Jörg; Espinoza, Carlos et al. (2018) Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma. JCI Insight 3:
Wang, Qing; Yan, Ran; Pinnell, Nancy et al. (2018) Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development. Blood 132:1279-1292
McDermott, Sarah C; Rodriguez-Ramirez, Christie; McDermott, Sean P et al. (2018) FGFR signaling regulates resistance of head and neck cancer stem cells to cisplatin. Oncotarget 9:25148-25165
Hartlerode, Andrea J; Regal, Joshua A; Ferguson, David O (2018) Reversible mislocalization of a disease-associated MRE11 splice variant product. Sci Rep 8:10121

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