The Mount Sinai School of Medicine proposes a training program in cancer biology for predoctoral fellows. A peer-reviewed predoctoral training program sponsored by the USAMRMC and focusing on breast cancer research was established three years ago at Mount Sinai. That initial program is being expanded to encompass a laboratory-based, multi-disciplinary program in cancer biology. Five predoctoral trainees would be supported by the training program. The training faculty consists of 29 preceptors from 11 departments and centers throughout Mount Sinai. Of these faculty, 60% have peer-reviewed support from extramural agencies for cancer-related studies. Predoctoral trainees will be sponsored for three to four years. The curriculum for the predoctoral trainees involves advanced course work in both basic and clinical cancer biology. All trainees will participate in regular conferences which will utilize the superb clinical resources at Mount Sinai and will further expose trainees to clinical aspects of cancer. Mount Sinai's continued commitment to cancer research, evidenced by the significant amount of physical and financial support dedicated to cancer research and the increasing number of investigators with cancer-related interests, combined with the success of the Breast Cancer Training Program, has led to this plan for a multi-disciplinary training program. This training program combines research in the biology of cancer with curriculum that challenges trainees to consider how their research may be translated into improvements in the diagnosis and treatment of cancer. The trainees will work closely with faculty who will be drawn from throughout Mount Sinai ensuring that this research is both comprehensive in scope and related to practical issues faced by physicians in preventing and treating cancer.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA078207-04
Application #
6513243
Study Section
Subcommittee G - Education (NCI)
Program Officer
Eckstein, David J
Project Start
1999-07-20
Project End
2004-04-30
Budget Start
2002-05-01
Budget End
2003-04-30
Support Year
4
Fiscal Year
2002
Total Cost
$136,764
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
114400633
City
New York
State
NY
Country
United States
Zip Code
10029
D'Avola, Delia; Villacorta-Martin, Carlos; Martins-Filho, Sebastiao N et al. (2018) High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma. Sci Rep 8:11570
Sonoshita, Masahiro; Scopton, Alex P; Ung, Peter M U et al. (2018) A whole-animal platform to advance a clinical kinase inhibitor into new disease space. Nat Chem Biol 14:291-298
Labgaa, Ismail; Villacorta-Martin, Carlos; D'Avola, Delia et al. (2018) A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma. Oncogene 37:3740-3752
Bane, Octavia; Hectors, Stefanie J; Wagner, Mathilde et al. (2018) Accuracy, repeatability, and interplatform reproducibility of T1 quantification methods used for DCE-MRI: Results from a multicenter phantom study. Magn Reson Med 79:2564-2575
Yadav, Rajesh K; Jablonowski, Carolyn M; Fernandez, Alfonso G et al. (2017) Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in S. pombe. Elife 6:
Kenny, T C; Hart, P; Ragazzi, M et al. (2017) Selected mitochondrial DNA landscapes activate the SIRT3 axis of the UPRmt to promote metastasis. Oncogene 36:4393-4404
Kenny, Timothy C; Germain, Doris (2017) mtDNA, Metastasis, and the Mitochondrial Unfolded Protein Response (UPRmt). Front Cell Dev Biol 5:37
Chernyavskaya, Yelena; Mudbhary, Raksha; Zhang, Chi et al. (2017) Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Development 144:2925-2939
Craig, Amanda J; von Felden, Johann; Villanueva, Augusto (2017) Molecular profiling of liver cancer heterogeneity. Discov Med 24:117-125
Lin, Su-Jiun; O'Connell, Matthew J (2017) DNA Topoisomerase II modulates acetyl-regulation of cohesin-mediated chromosome dynamics. Curr Genet 63:923-930

Showing the most recent 10 out of 96 publications