The goal of this program is to continue to provide broad-based interdisciplinary cancer research training for five predoctoral and five postdoctoral fellows. Trainees funded by this program will work with two faculty members whose complementary research interests lie in basic sciences, clinical research or population based sciences. In order to obtain funding through this training grant, fellows must submit research proposals relevant to the etiology or treatment of cancer that draw upon expertise found in two or more disciplines. Applications are judged on the research project, cancer relevance, interdisciplinary training potential and the applicants'qualifications. This training program is the centerpiece of an initiative in interdisciplinary cancer research at the Fred Hutchinson Cancer Research Center (FHCRC) and the University of Washington (UW). The long-term goal is to increase the pool of investigators who have training and expertise in cross-disciplinary applications of the rapidly expanding knowledge base in biomedical science relevant to cancer and other human diseases. The research experience will be supported by training in grant and manuscript writing, monthly interdisciplinary research meetings, a wide variety of seminars and informal group meetings. Trainees will meet annually with the grant Steering Committee and present their work annually at a research colloquium. The Steering Committee will also meet annually with mentors and monitor the interdisciplinary training components. An additional component of this program is support of predoctoral students who will obtain an M.S. degree in Epidemiology, concurrent with their Ph.D. training in a basic science. A formal Dual Degree program has been established at UW to allow this interdisciplinary training in an efficient manner. Trainees will be recruited both from the pool of pre- and postdoctoral trainees presently working at the two institutions, as well as from trainees who apply to this innovative program through mailings, informational booths at national meetings, and our web site.

Public Health Relevance

This interdisciplinary training program will increase the pool of cancer researchers with a broad knowledge of the causes and treatments of cancer using basic science, clinical and epidemiological tools. Such well trained scientists will be well poised to make breakthroughs in the eradication of this deadly disease.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA080416-12
Application #
7937930
Study Section
Subcommittee G - Education (NCI)
Program Officer
Lim, Susan E
Project Start
1998-08-11
Project End
2014-08-31
Budget Start
2010-09-01
Budget End
2011-08-31
Support Year
12
Fiscal Year
2010
Total Cost
$460,126
Indirect Cost
Name
University of Washington
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Bender Ignacio, Rachel A; Madison, Amy T; Moshiri, Ata et al. (2018) A Population-based Study of Perinatal Infection Risk in Women with and without Systemic Lupus Erythematosus and their Infants. Paediatr Perinat Epidemiol 32:81-89
Ferreccio, Amy; Mathieu, Julie; Detraux, Damien et al. (2018) Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal. Cell Cycle 17:535-549
Gupta, Amitabha; Evans, Rena K; Koch, Lori B et al. (2018) Purification of kinetochores from the budding yeast Saccharomyces cerevisiae. Methods Cell Biol 144:349-370
Oseso, Linda N; Chiao, Elizabeth Y; Ignacio, Rachel A Bender (2018) Evaluating Antiretroviral Therapy Initiation in HIV-Associated Malignancy: Is There Enough Evidence to Inform Clinical Guidelines? J Natl Compr Canc Netw 16:927-932
Poudel, Kumud R; Roh-Johnson, Minna; Su, Allen et al. (2018) Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis. Dev Cell 45:738-752.e6
LlaurĂ³, Aida; Hayashi, Hanako; Bailey, Megan E et al. (2018) The kinetoplastid kinetochore protein KKT4 is an unconventional microtubule tip-coupling protein. J Cell Biol 217:3886-3900
Matreyek, Kenneth A; Starita, Lea M; Stephany, Jason J et al. (2018) Multiplex assessment of protein variant abundance by massively parallel sequencing. Nat Genet 50:874-882
Stewart, Mikaela D; Zelin, Elena; Dhall, Abhinav et al. (2018) BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes. Proc Natl Acad Sci U S A 115:1316-1321
Suzuki, Aussie; Gupta, Amitabha; Long, Sarah K et al. (2018) A Kinesin-5, Cin8, Recruits Protein Phosphatase 1 to Kinetochores and Regulates Chromosome Segregation. Curr Biol 28:2697-2704.e3
Munson, Paul; Liu, Yi; Bratt, Debra et al. (2018) Therapeutic conserved elements (CE) DNA vaccine induces strong T-cell responses against highly conserved viral sequences during simian-human immunodeficiency virus infection. Hum Vaccin Immunother 14:1820-1831

Showing the most recent 10 out of 177 publications