This Research Training Program in Surgical Oncology is intended to train young surgeon-scientists who will pursue research and teaching careers in Surgical Oncology in academic institutions nationwide. The two-year postdoctoral program optimizes the ability of the trainees to relate modern molecular biology and other basic sciences to contemporary clinical problems. Research training is accomplished through four areas of experience: 1) required core curriculum, 2) mentor-directed laboratory training in one of six areas of oncologic research, 3) basic and clinical science-oriented interactive seminars, and 4) attendance at national scientific meetings and symposia. All Core Faculty mentors have active, funded laboratories, a broad base of experience in oncology-related basic research and prior mentoring experience. Their particular research strengths include chemoprevention, immunology/immunotherapy, molecular biology/gene therapy, molecular biomarkers, applied pharmacology, and radiation biology/radiotherapy. These mentors will ensure that sophisticated technologies are available to all trainees. Other Participating Faculty provides basic and/or clinical expertise that enhances the translational aspects of the training program. The Executive Committee provides administrative guidance to the Program Director, evaluates program progress and trainee applications, and suggests direction for future programmatic areas. The Trainee Advisory Committee consists of a Core Faculty Mentor and an additional Participating Faculty with appropriate basic and clinical research expertise. The External Review Committee provides for independent, extramural review of the program content and process. The UAB Department of Surgery offers trainees in all surgical subspecialties a unique opportunity to receive expert training in the basic, translational and clinical sciences. Funding of this T32 Training Program will enable these trainees to pursue two years of uninterrupted study of oncologic problems and will encourage these young surgeon-scientists to pursue important problems in Surgical Oncology throughout their career.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA091078-03
Application #
6776340
Study Section
Subcommittee G - Education (NCI)
Program Officer
Eckstein, David J
Project Start
2002-07-01
Project End
2007-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
3
Fiscal Year
2004
Total Cost
$340,504
Indirect Cost
Name
University of Alabama Birmingham
Department
Surgery
Type
Schools of Medicine
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Gao, Rebecca W; Teraphongphom, Nutte; de Boer, Esther et al. (2018) Safety of panitumumab-IRDye800CW and cetuximab-IRDye800CW for fluorescence-guided surgical navigation in head and neck cancers. Theranostics 8:2488-2495
Garner, Evan F; Williams, Adele P; Stafman, Laura L et al. (2018) FTY720 Decreases Tumorigenesis in Group 3 Medulloblastoma Patient-Derived Xenografts. Sci Rep 8:6913
Bownes, Laura V; Stafman, Laura L; Maizlin, Ilan I et al. (2018) Socioeconomic disparities affect survival in malignant ovarian germ cell tumors in AYA population. J Surg Res 222:180-186.e3
Garner, Evan F; Stafman, Laura L; Williams, Adele P et al. (2018) UAB30, a novel RXR agonist, decreases tumorigenesis and leptomeningeal disease in group 3 medulloblastoma patient-derived xenografts. J Neurooncol 140:209-224
Stafman, Laura L; Mruthyunjayappa, Smitha; Waters, Alicia M et al. (2018) Targeting PIM kinase as a therapeutic strategy in human hepatoblastoma. Oncotarget 9:22665-22679
Prince, Andrew C; Moore, Lindsay S; Tipirneni, Kiranya E et al. (2018) Evaluation of optical imaging agents in a fluorescence-guided surgical model of head and neck cancer. Surg Oncol 27:225-230
Stafman, Laura L; Maizlin, Ilan I; Dellinger, Matthew et al. (2018) Disparities in fertility-sparing surgery in adolescent and young women with stage I ovarian dysgerminoma. J Surg Res 224:38-43
Stafman, Laura L; Williams, Adele P; Garner, Evan F et al. (2018) Targeting PIM Kinases Affects Maintenance of CD133 Tumor Cell Population in Hepatoblastoma. Transl Oncol 12:200-208
Gao, Rebecca W; Teraphongphom, Nutte T; van den Berg, Nynke S et al. (2018) Determination of Tumor Margins with Surgical Specimen Mapping Using Near-Infrared Fluorescence. Cancer Res 78:5144-5154
Williams, Adele P; Waters, Alicia M; Stewart, Jerry E et al. (2018) A novel retinoid X receptor agonist, UAB30, inhibits rhabdomyosarcoma cells in vitro. J Surg Res 228:54-62

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