This Research Training Program in Surgical Oncology is intended to provide mentor-based training to young surgeon-scientists who will pursue research and teaching careers in Surgical Oncology. The two year postdoctoral program optimizes the ability of the trainees to translate modern molecular biology and other basic sciences to contemporary clinical problems. In the past five years our institution has developed an outstanding laboratory-based training program for academic surgical oncologists successfully training ten individuals who are now pursuing academic careers in different institutions throughout the country. Our goal is to continue this Program, while improving its attributes, to maximize the potential of our trainees to develop their own independent Surgical Oncology translational research efforts. Research training is accomplished through four areas of experience: 1) required core curriculum, 2) mentor-directed laboratory training in one of six areas of oncologic research, 3) basic and clinical science- oriented interactive seminars, and 4) attendance at national scientific meetings. All Core Faculty mentors have active, funded laboratories, and provide a broad base of experience in oncology-related basic research and prior mentoring experience. Their particular research strengths include chemoprevention, immunology, molecular biology/gene therapy, molecular biomarkers, applied pharmacology, and radiation biology. The Executive Committee provides administrative guidance to the Program Director, evaluates program progress and trainee applications, and suggests future directions. The Trainee Advisory Committee consists of a Core Faculty Mentor and additional Participating Faculty with appropriate research expertise. The External Review Committee provides for independent, extramural review of the program content and process. The UAB Department of Surgery offers trainees in all surgical subspecialties a unique opportunity to receive expert training in the basic and translational sciences. Funding of this Program will enable these trainees to pursue two years of uninterrupted study of fundamental Surgical Oncology problems while encouraging these surgeon-scientists to enter active academic careers with an emphasis on translational research that will undoubtedly impact the quality of cancer patient care in our country.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA091078-08
Application #
7648110
Study Section
Subcommittee G - Education (NCI)
Program Officer
Damico, Mark W
Project Start
2001-04-01
Project End
2012-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
8
Fiscal Year
2009
Total Cost
$348,990
Indirect Cost
Name
University of Alabama Birmingham
Department
Surgery
Type
Schools of Medicine
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Tipirneni, Kiranya E; Zhang, Shaoyan; Cho, Do-Yeon et al. (2018) Submucosal gland mucus strand velocity is decreased in chronic rhinosinusitis. Int Forum Allergy Rhinol 8:509-512
Foreman, Paul M; Jackson, Bradford E; Singh, Karan P et al. (2018) Postoperative radiosurgery for the treatment of metastatic brain tumor: Evaluation of local failure and leptomeningeal disease. J Clin Neurosci 49:48-55
Gao, Rebecca W; Teraphongphom, Nutte; de Boer, Esther et al. (2018) Safety of panitumumab-IRDye800CW and cetuximab-IRDye800CW for fluorescence-guided surgical navigation in head and neck cancers. Theranostics 8:2488-2495
Garner, Evan F; Williams, Adele P; Stafman, Laura L et al. (2018) FTY720 Decreases Tumorigenesis in Group 3 Medulloblastoma Patient-Derived Xenografts. Sci Rep 8:6913
Bownes, Laura V; Stafman, Laura L; Maizlin, Ilan I et al. (2018) Socioeconomic disparities affect survival in malignant ovarian germ cell tumors in AYA population. J Surg Res 222:180-186.e3
Garner, Evan F; Stafman, Laura L; Williams, Adele P et al. (2018) UAB30, a novel RXR agonist, decreases tumorigenesis and leptomeningeal disease in group 3 medulloblastoma patient-derived xenografts. J Neurooncol 140:209-224
Stafman, Laura L; Mruthyunjayappa, Smitha; Waters, Alicia M et al. (2018) Targeting PIM kinase as a therapeutic strategy in human hepatoblastoma. Oncotarget 9:22665-22679
Prince, Andrew C; Moore, Lindsay S; Tipirneni, Kiranya E et al. (2018) Evaluation of optical imaging agents in a fluorescence-guided surgical model of head and neck cancer. Surg Oncol 27:225-230
Stafman, Laura L; Maizlin, Ilan I; Dellinger, Matthew et al. (2018) Disparities in fertility-sparing surgery in adolescent and young women with stage I ovarian dysgerminoma. J Surg Res 224:38-43
Stafman, Laura L; Williams, Adele P; Garner, Evan F et al. (2018) Targeting PIM Kinases Affects Maintenance of CD133 Tumor Cell Population in Hepatoblastoma. Transl Oncol 12:200-208

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