Abstract

EXCEED THE SPACE PROVIDED. PERFORMANCE SITE(S) (organization, city, state) Medical College of Virginia Campus of Virginia Commonwealth University KEY PERSONNEL. See instructions on Page Name Dewey, W. Aceto, M. Balster, R. Beardsley, P. Cabral, G. Damaj, M.I. DeLorenzo, R. Eissenberg, T. Ellis, E. Glennon, R. Haller, D. Harris, L. PHS 398 (Rev. 4/98) 11. Use continuation pages as neededto provide the required information in the format shown below. Organization Role on Project Pharmacol/Toxicol Director/Advisor Pharmacol/Toxicol Advisor Pharmacol/Toxicol Admin. Committee/Advisor Pharmacol/Toxicol Advisor Microbiology Advisor .Pharmacol/Toxicol Advisor Neurology Advisor Psychology Advisor Pharmacol/Toxicol Advisor Medicinal Chemistry Advisor Psychiatry Advisor Pharmacol/Toxicol Co-Director/Advisor Page 2 Number pages consecutively at the bottom throughout the application. Do not use suffixes such as 3a, 3b. ========================================Section End===========================================

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Institutional National Research Service Award (T32)
Project #
5T32DA007027-30
Application #
6940747
Study Section
Special Emphasis Panel (ZDA1-RXL-E (07))
Program Officer
Lawrence, Diane M
Project Start
1976-07-01
Project End
2006-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
30
Fiscal Year
2005
Total Cost
$635,358
Indirect Cost

  Institution

Name
Virginia Commonwealth University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
105300446
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

Donvito, Giulia; Nass, Sara R; Wilkerson, Jenny L et al. (2018) The Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain. Neuropsychopharmacology 43:52-79
Wilkerson, Jenny L; Curry, Zachary A; Kinlow, Pamela D et al. (2018) Evaluation of different drug classes on transient sciatic nerve injury-depressed marble burying in mice. Pain 159:1155-1165
Hill, Rob; Disney, Alex; Conibear, Alex et al. (2018) The novel ?-opioid receptor agonist PZM21 depresses respiration and induces tolerance to antinociception. Br J Pharmacol 175:2653-2661
Kyte, S Lauren; Toma, Wisam; Bagdas, Deniz et al. (2018) Nicotine Prevents and Reverses Paclitaxel-Induced Mechanical Allodynia in a Mouse Model of CIPN. J Pharmacol Exp Ther 364:110-119
Johnson, Amy R; Banks, Matthew L; Selley, Dana E et al. (2018) Amphetamine maintenance differentially modulates effects of cocaine, methylenedioxypyrovalerone (MDPV), and methamphetamine on intracranial self-stimulation and nucleus accumbens dopamine in rats. Neuropsychopharmacology 43:1753-1762
Hill, Rob; Dewey, William L; Kelly, Eamonn et al. (2018) Oxycodone-induced tolerance to respiratory depression: reversal by ethanol, pregabalin and protein kinase C inhibition. Br J Pharmacol 175:2492-2503
Jacob, Joanna C; Sakakibara, Kensuke; Mischel, Ryan A et al. (2018) Ethanol Reversal of Oxycodone Tolerance in Dorsal Root Ganglia Neurons. Mol Pharmacol 93:417-426
Kyte, S Lauren; Gewirtz, David A (2018) The Influence of Nicotine on Lung Tumor Growth, Cancer Chemotherapy, and Chemotherapy-Induced Peripheral Neuropathy. J Pharmacol Exp Ther 366:303-313
Mischel, Ryan A; Dewey, William L; Akbarali, Hamid I (2018) Tolerance to Morphine-Induced Inhibition of TTX-R Sodium Channels in Dorsal Root Ganglia Neurons Is Modulated by Gut-Derived Mediators. iScience 2:193-209
Shin, Myungsun; Snyder, Helena W; Donvito, Giulia et al. (2018) Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo. Mol Pharm 15:721-728

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