EXCEED THE SPACE PROVIDED. The Division of Substance Abuse (DSA), Department of Psychiatry at Yale University School of Medicine requests a 5 year renewalperiod for its post-doctoral Drug Abuse Clinical ResearchTraining Program (CRTP) to support a total of 4 physicians and Ph.D. psychologists per year. Post-doctoral trainees will spend two to three years at Yale to obtain clinical and research training while being mentored by faculty investigators whose interests range from molecular neurobiology and genetics to pharmacologic and behavioral treatments and psychiatric epidemiology and health services research. With over 30 externally funded research projects and 28 full-time faculty, the central theme of our research program is the development and evaluation of innovative pharmacologic and behavioral treatments for substance abusers. Our multi-disciplinary program enables us to conduct research that moves rapidly and in both directions from preclinical projects ('bench') to clinical studies ('bedside'and 'community'). The overall success of the program is evidenced by the high proportion of trainees continuing in academic and clinical research careers after program completion and their publication record and continued involvement in NIH-funded clinical research. Changes implemented over the past two years and proposed in this application further strengthen the program. The main purpose of the CRTP is to provide post-doctoral trainees the opportunity to devote virtually full-time effort during the initial phase of their careers to developing the skills and experience needed to becomeindependent drug abuse clinical researchers and clinician scientists. Prospective trainees will identify a faculty mentor and develop a proposed training plan as part of the application procedure. During the training program, trainees participate in seminars on drug abuse clinical research and treatment, biostatistics and research design, and responsible conduct of scientific research. Under the supervisionof a faculty mentor, trainees gain experience in all aspects of clinical research, from initial project conceptualization and design, through study implementation, data analysis and manuscript preparation. Beginning early in the first year of the program, each trainee is expected to develop, implement and complete all phases of an independent research project, which serves as a base for future drug abuse clinical research. PERFORMANCE SITE ========================================Section End===========================================
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