The overall long-term goal of the UW Voice Research Training Program is to foster the development of translational research skills in future leaders in the field of voice science. We will provide promising predoctoral students and postdoctoral fellows with comprehensive laboratory and clinical research experiences, as well as exposure to a curriculum in clinical trials, hypothesis-based research design, management, ethics, and data analysis. This is a novel training program that addresses the need for translational research education and experience by integration of both a basic science mentor and a secondary clinical mentor. The program capitalizes on existing university resources to build an outstanding voice program for pre-and postdoctoral fellows, which is not matched elsewhere. In addition, the training program offers medical students a short-term summer research opportunity, to encourage future clinicians to become physician-scientists in the field of voice research. All trainees will be exposed to a unique program not typically found in doctoral programs. The current situation in most education centers is that laryngologists and speech pathologists interested in voice are getting separate training which creates an artificial obstacle to bridge th gap necessary in translational research. The program includes a pool of experienced, extramurally funded trainers from a variety of voice-related disciplines including surgery, biomedical engineering, chemical engineering and communicative disorders; and incorporates effective assessment processes, a plan to promote diversity by recruiting and retaining both women and minorities, and a solid plan for training in the responsible conduct of research. The combination of training in voice science with a multidisciplinary focus and translational application will make a contribution to future generations of scientists. The proposed training program is enriched by collaboration with already existing training elements at the University of Wisconsin, including the UW Institute for Clinical and Translational Research. The program is currently finishing its fourth successful year and this application represents a competing renewal with a request for five additional years of funding to maintain positions for five predoctoral trainees, two post-doctoral trainees and two short-term trainees each year. The program has demonstrated tremendous success in filling all available slots through a well qualified applicant pool and a multidisciplinary group of trainers. All but one trainee who has finished the program has pursued an academic research career or intends to pursue an academic research career. Other early indicators of success of the program include three individual F31 fellowships awarded to past trainees and productive publication and presentation records.

Public Health Relevance

Voice disorders affect approximately 7.5 million Americans. However, there are not a sufficient number of individuals with the expertise and training to perform high quality translational research that will result in successful treatments for these disorders. The University of Wisconsin (UW) Voice Research Training Program is training graduate students as well as individuals with PhDs and MDs to lead successful academic careers with a focus on translational research in voice.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Institutional National Research Service Award (T32)
Project #
5T32DC009401-08
Application #
9095159
Study Section
Special Emphasis Panel (ZDC1)
Program Officer
Rivera-Rentas, Alberto L
Project Start
2008-07-01
Project End
2019-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
8
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Surgery
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Kletzien, Heidi; Macdonald, Cameron L; Orne, Jason et al. (2018) Comparison Between Patient-Perceived Voice Changes and Quantitative Voice Measures in the First Postoperative Year After Thyroidectomy: A Secondary Analysis of a Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg 144:995-1003
Krekeler, Brittany N; Leverson, Glen; Connor, Nadine P (2018) Tongue exercise and ageing effects on morphological and biochemical properties of the posterior digastric and temporalis muscles in a Fischer 344 Brown Norway rat model. Arch Oral Biol 89:37-43
Krekeler, Brittany N; Wendt, Elizabeth; Macdonald, Cameron et al. (2018) Patient-Reported Dysphagia After Thyroidectomy: A Qualitative Study. JAMA Otolaryngol Head Neck Surg 144:342-348
Kletzien, Heidi; Russell, John A; Leverson, Glen et al. (2018) Effect of neuromuscular electrical stimulation frequency on muscles of the tongue. Muscle Nerve 58:441-448
Rosen, Sarah P; Abdelhalim, Suzan M; Jones, Corinne A et al. (2018) Effect of Body Position on Pharyngeal Swallowing Pressures Using High-Resolution Manometry. Dysphagia 33:389-398
Kletzien, Heidi; Hare, Allison J; Leverson, Glen et al. (2018) Age-related effect of cell death on fiber morphology and number in tongue muscle. Muscle Nerve 57:E29-E37
Cullins, Miranda J; Krekeler, Brittany N; Connor, Nadine P (2018) Differential impact of tongue exercise on intrinsic lingual muscles. Laryngoscope 128:2245-2251
Grant, Laura M; Barth, Kelsey J; Muslu, Cagla et al. (2018) Noradrenergic receptor modulation influences the acoustic parameters of pro-social rat ultrasonic vocalizations. Behav Neurosci 132:269-283
Krekeler, Brittany N; Broadfoot, Courtney K; Johnson, Stephen et al. (2018) Patient Adherence to Dysphagia Recommendations: A Systematic Review. Dysphagia 33:173-184
Devine, Erin E; Hoffman, Matthew R; McCulloch, Timothy M et al. (2017) Evaluation of type II thyroplasty on phonatory physiology in an excised canine larynx model. Laryngoscope 127:396-404

Showing the most recent 10 out of 69 publications