Progress towards understanding mechanisms of hearing, and the treatment of hearing deficits, requires an integrated effort from multiple disciplines within the field of hearing research. The Center for Hearing Research (CHR) at the University of California, Irvine (UCI) maintains an interdisciplinary training program that takes advantage of the breadth and depth of hearing research at UCI to train new scientists broadly across multiple disciplines as well as deeply in one. The 17 training faculty in CHR span six departments in four Schools (Biological Sciences, Engineering, Medicine and Social Sciences) with research interests that cover a broad range of levels (genes, molecules, cells, systems and behavior) and experimental approaches (cell and molecular biology, neurophysiology, psychoacoustics, computation, human imaging, medical devices). Thus, CHR is well-positioned to offer interdisciplinary training. We request support for three predoctoral students and two postdoctoral researchers including medical residents from Otolaryngology. The didactic core of the training program is a course in Auditory Neuroscience, which covers the auditory system from cells to psychoacoustics, the cochlear to the cortex, and basic and clinical aspects. Mandatory features of the training program that encourage interdisciplinary interactions are participation in all CHR activities (e.g., seminar series, journal club and two annual conferences) required oral and poster presentations to scientifically diverse audiences on three occasions per year, and regular meetings with basic and clinical scientists. The normal period of support is two years for pre- and post-doctoral trainees (1-2 years for residents). Predoctoral trainees normally enter the program in their second year of graduate study and are required to take a course on grant writing and submit an NRSA proposal. The program is managed by the Program Director and an Executive Committee, and will foster development of trainees' intellectual, technical and professional skills needed to pursue successful careers in hearing research.

Public Health Relevance

To fully understand how we hear, and design effective treatments for hearing deficits, requires knowledge of multiple disciplines, such as biology, medicine and engineering. This program trains junior scientists to be experts in one discipline and familiar with several, so that they are able to focus the tools and techniques of multiple disciplines on the problems to be solved.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Institutional National Research Service Award (T32)
Project #
5T32DC010775-10
Application #
9719809
Study Section
Special Emphasis Panel (ZDC1)
Program Officer
Rivera-Rentas, Alberto L
Project Start
2010-07-01
Project End
2020-06-30
Budget Start
2019-07-01
Budget End
2020-06-30
Support Year
10
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of California Irvine
Department
Other Basic Sciences
Type
Schools of Arts and Sciences
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92617
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Askew, Caitlin; Intskirveli, Irakli; Metherate, Raju (2017) Systemic Nicotine Increases Gain and Narrows Receptive Fields in A1 via Integrated Cortical and Subcortical Actions. eNeuro 4:
McClaskey, Carolyn M (2017) Standard-interval size affects interval-discrimination thresholds for pure-tone melodic pitch intervals. Hear Res 355:64-69
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Rotschafer, Sarah E; Marshak, Sonya; Cramer, Karina S (2015) Deletion of Fmr1 alters function and synaptic inputs in the auditory brainstem. PLoS One 10:e0117266

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