EXCEED THE SPACE PROVIDED. The Academic Nephrology Training Program at the University of California, San Francisco (UCSF) provides intensive research training for individuals interested in academic careers in nephrology or allied scientific subjects. A broad range of training opportunities is available in areas such as basic renal physiology, cellular and molecular biology of vascular smooth muscle cell regulation, pathogenesis and molecular basis of glomerular disease, cellular and molecular basis of hypertension, and epidemiology and outcomes in renal disease. The Program has been continuouslyfunded by the NIH for the past 26 years and has been the major source of support for the trainingof nephrology fellows in scientific research at UCSF. The proposed number of trainees for 2001-2006 will be 7 each year, the same number of positions as for the previous period (1996- 2001). There will be 4 positions for trainees with experience in adult nephrology and three positions for trainees in pediatric urology and/or nephrology. The majority of positions for the overall program will be filled with M.D. candidates, but the Program will admit qualified PhD candidates as well. Final selection for scientific training funded by this training grant will be based on clear evidence of interest in pursuit of a re- search career based on discussions with the faculty. Fellows will be expected to complete 3 years of research before pursuingan academic career in nephrology. The program will maintain its strong basic science training by faculty in nephrology, pediatrics, urology, anatomy, physiology and biochemistry and will add formal training in clinical research as an option for nephrology and urology fellows who are qualified to enter this training. The new curriculum will offer a Master in Clinical Research or a Certificate in Clinical Research to clinical research fellows before they pursue their projects. There is still an ongoing need for training of academic nephrologists due to the wholly inadequate understanding of the pathogenesis of many renal diseases and hypertension. This program has been highly successful in producing academic nephrologists, and this application requests continued funding for an additional5 years. PERFORMANCE SITE ========================================Section End===========================================
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