Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007233-20
Application #
2134747
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1976-07-01
Project End
1996-08-31
Budget Start
1995-09-01
Budget End
1996-08-31
Support Year
20
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Wilderman, P Ross; Jang, Hyun-Hee; Malenke, Jael R et al. (2014) Functional characterization of cytochromes P450 2B from the desert woodrat Neotoma lepida. Toxicol Appl Pharmacol 274:393-401
Baxter, Elizabeth Leigh; Zuris, John A; Wang, Charles et al. (2013) Allosteric control in a metalloprotein dramatically alters function. Proc Natl Acad Sci U S A 110:948-53
Tamir, Sagi; Zuris, John A; Agranat, Lily et al. (2013) Nutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugs. PLoS One 8:e61202
Wilderman, P Ross; Gay, Sean C; Jang, Hyun-Hee et al. (2012) Investigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzyme. FEBS J 279:1607-20
Kang, Guipeun; López-Peña, Ignacio; Oklejas, Vanessa et al. (2012) Förster resonance energy transfer as a probe of membrane protein folding. Biochim Biophys Acta 1818:154-61
Wilderman, P Ross; Halpert, James R (2012) Plasticity of CYP2B enzymes: structural and solution biophysical methods. Curr Drug Metab 13:167-76
Wu-Zhang, Alyssa X; Schramm, Cicely L; Nabavi, Sadegh et al. (2012) Cellular pharmacology of protein kinase M? (PKM?) contrasts with its in vitro profile: implications for PKM? as a mediator of memory. J Biol Chem 287:12879-85
Olson, Karen E; Muller, Ulrich F (2012) An in vivo selection method to optimize trans-splicing ribozymes. RNA 18:581-9
Nechushtai, Rachel; Conlan, Andrea R; Harir, Yael et al. (2012) Characterization of Arabidopsis NEET reveals an ancient role for NEET proteins in iron metabolism. Plant Cell 24:2139-54
Meluzzi, Dario; Olson, Karen E; Dolan, Gregory F et al. (2012) Computational prediction of efficient splice sites for trans-splicing ribozymes. RNA 18:590-602

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