This competitive renewal of a Training Program in Endocrinology, Diabetes and Metabolism (DK07352) was combined in 1988 from programs in Endocrinology funded in 1968 (07147) and Diabetes and Metabolism funded in 1979 (DK07352). The Program provides postdoctoral research training in Diabetes, Endocrinology and Metabolism for individuals with MD or PhD degrees, preparing trainees for academic careers as independent investigators and provides up to three years of laboratory research training. The faculty consists of 13 investigators funded with NIH R01 grants and/or other funds, 2 junior faculty members with R29 or R03 awards, 65 adjacent faculty in basic science departments and 33 clinical adjunct faculty members. The program is designed to provide trainees with: (i) all components of the scientific method, (ii) a focused approach to scientific investigation, (iii) experience with the most modern analytical tools and methodologies, and (iv) capability to develop as independent biomedical research scientists. The components of the Program include formal didactic course work, seminars and conferences, intra- and extra-mural scientific presentations, and a focused research experience in the laboratories of established investigators. The Program is Administered by the Steering Committee, chaired by the Program Director, which is responsible for the trainees' appointment and laboratory assignment, development of didactic curricula, review of trainees' initial project, and annual review of trainees' progress. Of particular note in the Program are the focused approach to training goals for each laboratory-based trainee, a strong commitment to provide maximal training duration, the uniform extramural funding of the independent investigators that serve as primary faculty, the productive training record of the training program, the presence of an enthusiastic and knowledgeable junior training faculty, the availability of adjunct faculty whose primary areas of basic science and/or clinical investigation are intimately tied to those of metabolism, diabetes and endocrinology, and the diversity of the faculty research programs which range from molecular endocrinology, and the diversity of the faculty research programs which range from molecular endocrinology to clinical research. Due to the program's popularity and success and the 87.8% increase in research funds awarded to our highly qualified faculty, we request to increase the size of the program from 6 to 8 fellows.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007352-25
Application #
6604118
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Hyde, James F
Project Start
1979-07-19
Project End
2004-06-30
Budget Start
2003-07-01
Budget End
2004-06-30
Support Year
25
Fiscal Year
2003
Total Cost
$333,387
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905
Chung, Jin Ook; Koutsari, Christina; Blachnio-Zablieska, Agnieszka Urszula et al. (2018) Effects of meal ingestion on intramyocellular ceramide concentrations and fractional de novo synthesis in humans. Am J Physiol Endocrinol Metab 314:E105-E114
Varghese, Ron T; Dalla Man, Chiara; Laurenti, Marcello C et al. (2018) Performance of individually measured vs population-based C-peptide kinetics to assess ?-cell function in the presence and absence of acute insulin resistance. Diabetes Obes Metab 20:549-555
Robinson, Matthew M; Lowe, Val J; Nair, K Sreekumaran (2018) Increased Brain Glucose Uptake After 12 Weeks of Aerobic High-Intensity Interval Training in Young and Older Adults. J Clin Endocrinol Metab 103:221-227
Dominelli, Paolo B; Ripoll, Juan G; Cross, Troy J et al. (2018) Sex differences in large conducting airway anatomy. J Appl Physiol (1985) 125:960-965
Limberg, Jacqueline K (2018) Glucose, insulin, and the carotid body chemoreceptors in humans. Physiol Genomics 50:504-509
Karanth, Santhosh; Adams, J D; Serrano, Maria de Los Angeles et al. (2018) A Hepatocyte FOXN3-? Cell Glucagon Axis Regulates Fasting Glucose. Cell Rep 24:312-319
Barbosa, Thales C; Kaur, Jasdeep; Holwerda, Seth W et al. (2018) Insulin increases ventilation during euglycemia in humans. Am J Physiol Regul Integr Comp Physiol 315:R84-R89
Schulze, Ryan J; Sathyanarayan, Aishwarya; Mashek, Douglas G (2017) Breaking fat: The regulation and mechanisms of lipophagy. Biochim Biophys Acta Mol Cell Biol Lipids 1862:1178-1187
Morgan-Bathke, Maria; Harteneck, Debra; Jaeger, Philippa et al. (2017) Comparison of Methods for Analyzing Human Adipose Tissue Macrophage Content. Obesity (Silver Spring) 25:2100-2107
Santosa, Sylvia; Bush, Nikki C; Jensen, Michael D (2017) Acute Testosterone Deficiency Alters Adipose Tissue Fatty Acid Storage. J Clin Endocrinol Metab 102:3056-3064

Showing the most recent 10 out of 137 publications