Abstract

The overall goal of this program is to recruit and train board eligible M.D.'s and postgraduate Ph.D.'s for academic and research careers in neuroendocrinology. Training faculty include clinical and basic science investigators with strengths in a broad range of topics in this rapidly expanding interdisciplinary field, and who offer trainees the opportunity to study neuroendocrine problems at the molecular, cellular, and systems level. Training program investigators have currently active research program on the neuroendocrine control of hypertension, growth metabolism, reproduction, rhythmic motor behaviors, gene regulation, and development. Specific projects available to trainees include hypothalamic and peripheral regulation of pituitary function, hormone synthesis and secretion hormone and neurotransmitter receptors, clinical evaluation of secretogogue and inhibitors, experimental therapeutic protocols, intracellular signalling, intracellular and central feedback systems, neural development and organization and electrochemical measurements of neural activity.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007646-09
Application #
2770313
Study Section
Special Emphasis Panel (SRC)
Program Officer
Margolis, Ronald N
Project Start
1990-09-01
Project End
2000-08-31
Budget Start
1998-09-01
Budget End
1999-08-31
Support Year
9
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
University of Virginia
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904

  Publications

Burt Solorzano, Christine M; Knudsen, Karen L; Anderson, Amy D et al. (2018) Insulin Resistance, Hyperinsulinemia, and LH: Relative Roles in Peripubertal Obesity-Associated Hyperandrogenemia. J Clin Endocrinol Metab 103:2571-2582
DeBoer, Mark D; Cherñavvsky, Daniel R; Topchyan, Katarina et al. (2016) Heart rate informed artificial pancreas system enhances glycemic control during exercise in adolescents with T1D. Pediatr Diabetes :
Hutchens, Eleanor G; Ramsey, Katherine A; Howard, Louisa C et al. (2016) Progesterone has rapid positive feedback actions on LH release but fails to reduce LH pulse frequency within 12 h in estradiol-pretreated women. Physiol Rep 4:
Culver, Silas A; Grober, Yuval; Ornan, David A et al. (2015) A Case for Conservative Management: Characterizing the Natural History of Radiographically Diagnosed Rathke Cleft Cysts. J Clin Endocrinol Metab 100:3943-8
Zhao, Lina; Fu, Zhuo; Wu, Jing et al. (2015) Inflammation-induced microvascular insulin resistance is an early event in diet-induced obesity. Clin Sci (Lond) 129:1025-36
van der Vinne, Vincent; Riede, Sjaak J; Gorter, Jenke A et al. (2014) Cold and hunger induce diurnality in a nocturnal mammal. Proc Natl Acad Sci U S A 111:15256-60
Collins, Jessicah S; Beller, Jennifer P; Burt Solorzano, Christine et al. (2014) Blunted day-night changes in luteinizing hormone pulse frequency in girls with obesity: the potential role of hyperandrogenemia. J Clin Endocrinol Metab 99:2887-96
Fu, Zhuo; Zhao, Lina; Aylor, Kevin W et al. (2014) Angiotensin-(1-7) recruits muscle microvasculature and enhances insulin's metabolic action via mas receptor. Hypertension 63:1219-27
Stolzenberg, Danielle S; Stevens, Jacqueline S; Rissman, Emilie F (2014) Histone deacetylase inhibition induces long-lasting changes in maternal behavior and gene expression in female mice. Endocrinology 155:3674-83
Anderson, Amy D; Solorzano, Christine M Burt; McCartney, Christopher R (2014) Childhood obesity and its impact on the development of adolescent PCOS. Semin Reprod Med 32:202-13

Showing the most recent 10 out of 60 publications