This training grant in developmental endocrinology and metabolism, now in its twentieth year, intends to provide funding for five postdoctoral students per year to engage in research training leading to independent careers in academic pediatric endocrinology. Trainees enter the program with either the MD, MD/PhD or occasionally the PhD degree. Training opportunities include basic laboratory investigations in neuroendocrinology including appetite regulation and energy balance, insulin action and carbohydrate regulation, calcium metabolism, thyroid biology, growth factor biology, and genomics/bioinformatics, as well as clinical research in carbohydrate metabolism, reproductive endocrinology, obesity, and medical informatics. The intended average duration of training is two years. In this competing application, in addition to the five postdoctoral positions, we also request 3 short term (10 week) predoctoral positions to fund trainees who engage in research, largely during medical school.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007699-25
Application #
7080423
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Hyde, James F
Project Start
1992-07-01
Project End
2007-06-30
Budget Start
2006-07-01
Budget End
2007-06-30
Support Year
25
Fiscal Year
2006
Total Cost
$175,386
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Majzoub, Joseph A; Topor, Lisa Swartz (2018) A New Model for Adrenarche: Inhibition of 3?-Hydroxysteroid Dehydrogenase Type 2 by Intra-Adrenal Cortisol. Horm Res Paediatr 89:311-319
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Swartz, Jonathan M; Ciarlo, Ryan; Guo, Michael H et al. (2017) A 46,XX Ovotesticular Disorder of Sex Development Likely Caused by a Steroidogenic Factor-1 (NR5A1) Variant. Horm Res Paediatr 87:191-195
Carswell, Jeremi M; Roberts, Stephanie A (2017) Induction and Maintenance of Amenorrhea in Transmasculine and Nonbinary Adolescents. Transgend Health 2:195-201
Stefater, M A; Inge, T H (2017) Bariatric Surgery for Adolescents with Type 2 Diabetes: an Emerging Therapeutic Strategy. Curr Diab Rep 17:62

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