The Cellular and Molecular Endocrinology Training Program at Johns Hopkins University seeks renewal funding. Since the last renewal period, training faculty have increased from 15 to 35, a new training site at the National Institutes of Health has been added, a new interdepartmental Division of Metabolism has been created, and significant new resources have been committed. The goal of the Interdepartmental Training Program is to expand the pool of well-trained and productive investigators in the biomedical sciences related to endocrinology. The Program Director works with a Steering Committee to choose candidates from two pools of talented individuals: 1) endocrine fellows who have completed one year of clinical training, and 2) M.D., M.D.&Ph.D. or Ph.D. applicants who have an interest in fundamental laboratory training. The program has been able to recruit the most qualified candidates through a process that stresses diversity. Selection is based not only on the individual's qualifications and interests, but also on their potential and commitment to applying fundamental science to clinical problems. The mentoring program is structured with a strong fundamental knowledge base that is individually tailored for basic and translational research in endocrinology. The training program consists of at least two years of research under the direction of the most qualified and talented mentors at Johns Hopkins and the National Institutes of Health in endocrinology and relevant disciplines. Trainees participate in an innovative didactic curriculum that consists of research seminars, data/journal clubs, and formal courses. Fellows will also be trained in the ethical conduct of research, have well defined milestones for accomplishing scientific goals, and have regular meetings with mentors, the steering committee and others in the scientific community. Training programs in written and oral communication and leadership are instituted as well as an evaluation system for fellows and mentors. The availability of an NIH-funded General Clinical Research Center and mentors with translational research protocols provides trainees with an opportunity to develop translational protocols that complement their laboratory studies. We are committed to nurturing a new cadre of faculty who will become leaders in the field of endocrinology research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
3T32DK007751-13S1
Application #
7888472
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Castle, Arthur
Project Start
1997-09-12
Project End
2012-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
13
Fiscal Year
2009
Total Cost
$31,510
Indirect Cost
Name
Johns Hopkins University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Zheng, Liwei; Cao, Yong; Ni, Shuangfei et al. (2018) Ciliary parathyroid hormone signaling activates transforming growth factor-? to maintain intervertebral disc homeostasis during aging. Bone Res 6:21
Pilla, Scott J; Dotimas, James R; Maruthur, Nisa M et al. (2018) Changes in metformin use and other antihyperglycemic therapies after insulin initiation in patients with type 2 diabetes. Diabetes Res Clin Pract 139:221-229
Qiu, Shuiqing; Vazquez, Juliana Torrens; Boulger, Erin et al. (2017) Hepatic estrogen receptor ? is critical for regulation of gluconeogenesis and lipid metabolism in males. Sci Rep 7:1661
Cao, Yong; Liao, Shenghui; Zeng, Hao et al. (2017) 3D characterization of morphological changes in the intervertebral disc and endplate during aging: A propagation phase contrast synchrotron micro-tomography study. Sci Rep 7:43094
Andrisse, Stanley; Childress, Shameka; Ma, Yaping et al. (2017) Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms. Endocrinology 158:531-544
Wang, Long; Xie, Liang; Tintani, Francis et al. (2017) Aberrant Transforming Growth Factor-? Activation Recruits Mesenchymal Stem Cells During Prostatic Hyperplasia. Stem Cells Transl Med 6:394-404
Xie, Liang; Tintani, Francis; Wang, Xiao et al. (2016) Systemic neutralization of TGF-? attenuates osteoarthritis. Ann N Y Acad Sci 1376:53-64
Salehi, Sajad; Adeshina, Ikeoluwa; Chen, Haolin et al. (2015) Developmental and endocrine regulation of kisspeptin expression in mouse Leydig cells. Endocrinology 156:1514-22
Mathioudakis, Nestoras; Sundaresh, Ram; Larsen, Alexandra et al. (2015) Expression of the pituitary stem/progenitor marker GFR?2 in human pituitary adenomas and normal pituitary. Pituitary 18:31-41
Wolf, Risa M; Steele, Kimberley E; Peterson, Leigh A et al. (2015) Lower Circulating C1q/TNF-Related Protein-3 (CTRP3) Levels Are Associated with Obesity: A Cross-Sectional Study. PLoS One 10:e0133955

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