Oregon State University (OSU), a land-, sea- and space-grant institution, has an active program in graduate training in environmental toxicology that has received support from the NIEHS training grant for 20 years. The success of this training program in Toxicology is due in part to the faculty and facilities supported by th two NIEHS-funded Centers, the Environmental Health Sciences Center (P30-ES00210), and the Marine/Freshwater Biomedical Sciences Center (P30-ES03850). Nine of the 15 Training Grant Faculty are members of one or both Centers. Trainees have access to all of the expertise associated with the research cores of both Centers and the capacity to utilize state-of-the-art technology in their toxicology research through the availability of the facility cores of both Centers. Additional training opportunities with clinical applications are provided through two Training Grant faculty at the Oregon Health Sciences University in Portland. All of the Training Grant faculty have active research programs in toxicology/environmental health supported in large part by NIEHS P01 and/or R01 grants. The focus of the Graduate Toxicology Program at OSU is the mode of action of environmental chemicals with an emphasis on xenobiotic metabolism. During the present grant period, recruitment of new faculty has allowed our program to expand to provide additional training opportunities in the fields of signal transduction and DNA repair. The success of the OSU trainees from this grant in academic government, and industrial careers and their contributions to the environmental health sciences have been outstanding. The quality of applicants to our Program continue to be high, and future trainees will continue to build on this record of achievement Several programmatic developments at OSU have strengthened the Toxicology Graduate Program and increased the breadth of training opportunities. These include formal of a new Department of Environmental and Molecular Toxicology, the relocation of the Linus Pauling Institute to Oregon State University, and the recruitment of several new faculty with research programs in the environmental health sciences. Our ability to recruit minority students to OSU, which will enrich the diversity of our Program, has been enhanced by the recent funding of an NIEHS grant for short-term research training support for minority students (T35- ES007316). This strong and continually improving training program will enable OSU to provide the broad interdisciplinary research training in toxicology essential for these trainees to become the future leaders in environmental health sciences research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Institutional National Research Service Award (T32)
Project #
2T32ES007060-21
Application #
2802533
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1979-07-01
Project End
2004-06-30
Budget Start
1999-07-01
Budget End
2000-06-30
Support Year
21
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Oregon State University
Department
Type
Organized Research Units
DUNS #
053599908
City
Corvallis
State
OR
Country
United States
Zip Code
97339
Denluck, Lindsay; Wu, Fan; Crandon, Lauren E et al. (2018) Reactive oxygen species generation is likely a driver of copper based nanomaterial toxicity. Environ Sci Nano 5:1473-1481
Piper, Brian J (2018) Mother of Berries, ACDC, or Chocolope: Examination of the Strains Used by Medical Cannabis Patients in New England. J Psychoactive Drugs 50:95-104
Ehrlich, Allison K; Pennington, Jamie M; Bisson, William H et al. (2018) TCDD, FICZ, and Other High Affinity AhR Ligands Dose-Dependently Determine the Fate of CD4+ T Cell Differentiation. Toxicol Sci 161:310-320
Titaley, Ivan A; Ogba, O Maduka; Chibwe, Leah et al. (2018) Automating data analysis for two-dimensional gas chromatography/time-of-flight mass spectrometry non-targeted analysis of comparative samples. J Chromatogr A 1541:57-62
Geier, Mitra C; Chlebowski, Anna C; Truong, Lisa et al. (2018) Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons. Arch Toxicol 92:571-586
Axton, Elizabeth Rose; Cristobal, Eleonso; Choi, Jaewoo et al. (2018) Metabolomics-Driven Elucidation of Cellular Nitrate Tolerance Reveals Ascorbic Acid Prevents Nitroglycerin-Induced Inactivation of Xanthine Oxidase. Front Pharmacol 9:1085
Bugel, Sean M; Tanguay, Robert L (2018) Multidimensional chemobehavior analysis of flavonoids and neuroactive compounds in zebrafish. Toxicol Appl Pharmacol 344:23-34
Garcia, Gloria R; Bugel, Sean M; Truong, Lisa et al. (2018) AHR2 required for normal behavioral responses and proper development of the skeletal and reproductive systems in zebrafish. PLoS One 13:e0193484
Roper, Courtney; Simonich, Staci L Massey; Tanguay, Robert L (2018) Development of a high-throughput in vivo screening platform for particulate matter exposures. Environ Pollut 235:993-1005
Haggard, Derik E; Noyes, Pamela D; Waters, Katrina M et al. (2018) Transcriptomic and phenotypic profiling in developing zebrafish exposed to thyroid hormone receptor agonists. Reprod Toxicol 77:80-93

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