Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Institutional National Research Service Award (T32)
Project #
5T32ES007075-19
Application #
2156177
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1978-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Berkeley
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
094878337
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Jump, Sarah M; Kung, Jenny; Staub, Richard et al. (2008) N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells. Biochem Pharmacol 75:713-24
Babiarz, Joshua E; Halley, Jeffrey E; Rine, Jasper (2006) Telomeric heterochromatin boundaries require NuA4-dependent acetylation of histone variant H2A.Z in Saccharomyces cerevisiae. Genes Dev 20:700-10
Staub, Richard E; Onisko, Bruce; Bjeldanes, Leonard F (2006) Fate of 3,3'-diindolylmethane in cultured MCF-7 human breast cancer cells. Chem Res Toxicol 19:436-42
Davies, Brandon S J; Wang, Helen S; Rine, Jasper (2005) Dual activators of the sterol biosynthetic pathway of Saccharomyces cerevisiae: similar activation/regulatory domains but different response mechanisms. Mol Cell Biol 25:7375-85
Gunn, Laura; Smith, Martyn T (2004) Emerging biomarker technologies. IARC Sci Publ :437-50
Staub, Richard E; Bjeldanes, Leonard F (2003) Convenient synthesis of 5,6,11,12,17,18- hexahydrocyclononal[1,2-b:4,5-b':7,8-b'']triindole, a novel phytoestrogen. J Org Chem 68:167-9
Brumaghim, Julia L; Li, Ying; Henle, Ernst et al. (2003) Effects of hydrogen peroxide upon nicotinamide nucleotide metabolism in Escherichia coli: changes in enzyme levels and nicotinamide nucleotide pools and studies of the oxidation of NAD(P)H by Fe(III). J Biol Chem 278:42495-504
Ho, Emily; Courtemanche, Chantal; Ames, Bruce N (2003) Zinc deficiency induces oxidative DNA damage and increases p53 expression in human lung fibroblasts. J Nutr 133:2543-8
Ho, Emily; Ames, Bruce N (2002) Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFkappa B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line. Proc Natl Acad Sci U S A 99:16770-5
Staub, Richard E; Feng, Chunling; Onisko, Bruce et al. (2002) Fate of indole-3-carbinol in cultured human breast tumor cells. Chem Res Toxicol 15:101-9

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