This is a renewal application for support of graduate training in Cellular and Molecular Biology within the Division of Biology and Biomedical Sciences at Washington University. Since 1973, all predoctoral education in the biological sciences at Washington University has been provided by the Division of Biology and Biomedical Sciences. The Division is a unique and nationally recognized administrative structure, the key feature of which is the absence of any departmental predoctoral programs: all predoctoral programs and degree-granting units in the biological sciences at this university are both interdisciplinary and interdepartmental. The Division was established with its own endowment more than 20 years ago in recognition of the increasingly interrelated nature of all aspects of research in the biomedical and biological sciences, and in order to facilitate cooperation among faculty in the interdisciplinary training of prospective biological scientists. It is in such a tradition that the current training grant is rooted; we intend to use the continuation of this training grant to promote the professional growth of students whose research interests lie in an interdisciplinary area of rapidly growing importance and productivity: cellular and molecular biology. In parallel we hope to foster interactions among faculty which in turn will provide unique research opportunities for students.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007200-24
Application #
2654706
Study Section
Cellular and Molecular Basis of Disease Review Committee (CMBD)
Project Start
1975-07-01
Project End
2000-06-30
Budget Start
1998-07-01
Budget End
1999-06-30
Support Year
24
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Washington University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Wang, Zhuo A; Li, Lucy X; Doering, Tamara L (2018) Unraveling synthesis of the cryptococcal cell wall and capsule. Glycobiology 28:719-730
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Verbaro, Daniel J; Sakurai, Nagisa; Kim, Byungil et al. (2018) Cutting Edge: The Histone Methyltransferase G9a Is Required for Silencing of Helper T Lineage-Associated Genes in Proliferating CD8 T Cells. J Immunol 200:3891-3896
Grither, Whitney R; Longmore, Gregory D (2018) Inhibition of tumor-microenvironment interaction and tumor invasion by small-molecule allosteric inhibitor of DDR2 extracellular domain. Proc Natl Acad Sci U S A 115:E7786-E7794
Wegscheid, Michelle L; Anastasaki, Corina; Gutmann, David H (2018) Human stem cell modeling in neurofibromatosis type 1 (NF1). Exp Neurol 299:270-280
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Berry, Kayla N; Kober, Daniel L; Su, Alvin et al. (2018) Limiting Respiratory Viral Infection by Targeting Antiviral and Immunological Functions of BST-2/Tetherin: Knowledge and Gaps. Bioessays 40:e1800086

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