The MIT Department of Biology is applying for continued support of its highly successful training program for graduate students in the biological sciences. The long term objective of the program is to prepare our students for independent professional careers in the life sciences, applying the tools of basic research to the questions of modern medicine and biology in both academic and industrial settings. The training program has several components: providing students with a solid foundation in the intellectual bases of modern biology; exposing students to the wide range of scientific questions and technical approaches now integral to the life sciences; teaching students the skills of experimental design, data analysis, and effective communication; and educating students in the ethical and social issues that are part of doing research. Ethical and social issues are explored in the context of several courses. In addition, in the second year of training, students take a special course designed specifically to cover issues related to the responsible conduct of research. The excellent students who enter our program are selected by a competitive process that includes a personal interview. The first semester of the program emphasizes formal courses. Students typically take three required courses designed to teach genetics, biochemistry, and methods of analysis, and one elective course selected from a wide range of choices. Students take three more elective courses in the spring semester. Beginning in the spring semester of the first year, students participate in three one-month laboratory rotations. At the end of the semester students choose a lab for their thesis research. Students can choose from any of the 60 laboratories in the Department, covering a wide variety of topics, including: biochemistry, bioinformatics, cancer biology, cell biology, computational biology, developmental biology, enzymology, genetics and medical genetics, genomics, immunology, microbiology, neurobiology, physiology, and systems biology. Throughout their graduate careers, students continue their education through departmental seminars, journal clubs, and special interest groups. We currently have twelve under-represented minority graduate students in the program and will continue our efforts to attract, recruit, and train qualified under-represented minority applicants. Our graduate students play major roles in the intellectual life and research efforts of the Department and go on to make substantive contributions to modern biology. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
2T32GM007287-31
Application #
6845616
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Zatz, Marion M
Project Start
1975-07-01
Project End
2010-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
31
Fiscal Year
2005
Total Cost
$2,050,258
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Perez, Dahlia E; Henle, Andrea M; Amsterdam, Adam et al. (2018) Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology. Pigment Cell Melanoma Res 31:604-613
Drosu, Natalia C; Edelman, Elazer R; Housman, David E (2018) Could antiretrovirals be treating EBV in MS? A case report. Mult Scler Relat Disord 22:19-21
Ray, Leah C; Das, Debasis; Entova, Sonya et al. (2018) Membrane association of monotopic phosphoglycosyl transferase underpins function. Nat Chem Biol 14:538-541
Kayatekin, Can; Amasino, Audra; Gaglia, Giorgio et al. (2018) Translocon Declogger Ste24 Protects against IAPP Oligomer-Induced Proteotoxicity. Cell 173:62-73.e9
Hilbert, Zoƫ A; Kim, Dennis H (2018) PDF-1 neuropeptide signaling regulates sexually dimorphic gene expression in shared sensory neurons of C. elegans. Elife 7:
Dubbury, Sara J; Boutz, Paul L; Sharp, Phillip A (2018) CDK12 regulates DNA repair genes by suppressing intronic polyadenylation. Nature 564:141-145
Romer, Katherine A; de Rooij, Dirk G; Kojima, Mina L et al. (2018) Isolating mitotic and meiotic germ cells from male mice by developmental synchronization, staging, and sorting. Dev Biol 443:19-34
Wesselhoeft, R Alexander; Kowalski, Piotr S; Anderson, Daniel G (2018) Engineering circular RNA for potent and stable translation in eukaryotic cells. Nat Commun 9:2629
Sabari, Benjamin R; Dall'Agnese, Alessandra; Boija, Ann et al. (2018) Coactivator condensation at super-enhancers links phase separation and gene control. Science 361:
Phizicky, David V; Berchowitz, Luke E; Bell, Stephen P (2018) Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis. Elife 7:

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