The objectives of the graduate training program in Cellular and Molecular Approaches to Behavior at Cornell University are to train students to combine cellular and molecular neurobiological tools with higher levels of analysis to understand the mechanistic bases underlying behavior. There is a growing appreciation of the necessary interactions between neurobiology and the behavioral sciences, and our students will be trained to be leaders in this new interface. The research areas represented by the core faculty include focus groups in the function of ion channels in neuronal signaling, molecular mechanisms of synaptic function and neuromodulation, neurodevelopment, neuropharmacology, sensory systems and animal communication, motor systems, and neuroethology. Fully equipped facilities for all of these areas are available to the students both in faculty laboratories and in a number of shared facilities. Six predoctoral students will each be supported for a maximum of two years; they are usually appointed at the beginning of their training in the Graduate Field of Neurobiology and Behavior. Most have completed a major in biological sciences, and have taken at least one course in neurobiology. These students are in the top 15th percentile on the graduate records examination, and nearly all have done research during their undergraduate education. All students must meet the general training requirements of the Field, which provides them with a broad training in both neurobiology and behavior. In addition, trainees in our program take a series of laboratory rotations, advanced lecture and laboratory courses to provide strength in cellular and molecular neurobiology. These are combined with journal clubs and weekly seminars which discuss recent advances in our field. Our students benefit from interactions with other academic programs at Cornell by completing the requirements for a Minor, usually in biochemistry, molecular biology, genetics, pharmacology, chemistry, applied physics, biophysics or psychology, which offer courses and seminars of interest. Relevance: Our students will be trained to use cellular and molecular approaches to study systems-level questions about how behavior is generated by neuronal interactions in discrete neural networks. With the rapid progress in genomics, we will soon know the molecular """"""""parts list"""""""" that makes a brain; the research supported by this grant will study how these parts work together to generate perception, locomotion and other behaviors. It should also provide insights into the causes and possible treatments for psychiatric and other behavioral diseases in humans. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
2T32GM007469-31A1
Application #
7286547
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Cole, Alison E
Project Start
1977-07-01
Project End
2012-06-30
Budget Start
2007-07-01
Budget End
2008-06-30
Support Year
31
Fiscal Year
2007
Total Cost
$244,633
Indirect Cost
Name
Cornell University
Department
Other Basic Sciences
Type
Schools of Arts and Sciences
DUNS #
872612445
City
Ithaca
State
NY
Country
United States
Zip Code
14850
Feng, Ni Y; Bass, Andrew H (2014) Melatonin action in a midbrain vocal-acoustic network. J Exp Biol 217:1046-57
Lawton, Kristy J; Wassmer, Taryn L; Deitcher, David L (2014) Conserved role of Drosophila melanogaster FoxP in motor coordination and courtship song. Behav Brain Res 268:213-21
Fergus, Daniel J; Shaw, Kerry L (2013) Circadian rhythms and period expression in the Hawaiian cricket genus Laupala. Behav Genet 43:241-53
Dillon, T Samuel; Fox, Laura C; Han, Crystal et al. (2013) 17?-estradiol enhances memory duration in the main olfactory bulb in CD-1 mice. Behav Neurosci 127:923-31
Abbinanti, Matthew D; Zhong, Guisheng; Harris-Warrick, Ronald M (2012) Postnatal emergence of serotonin-induced plateau potentials in commissural interneurons of the mouse spinal cord. J Neurophysiol 108:2191-202
Kisler, Kassandra; Kim, Brian N; Liu, Xin et al. (2012) Transparent Electrode Materials for Simultaneous Amperometric Detection of Exocytosis and Fluorescence Microscopy. J Biomater Nanobiotechnol 3:243-253
Gallant, Jason R; Hopkins, Carl D; Deitcher, David L (2012) Differential expression of genes and proteins between electric organ and skeletal muscle in the mormyrid electric fish Brienomyrus brachyistius. J Exp Biol 215:2479-94
Abbinanti, Matthew D; Harris-Warrick, Ronald M (2012) Serotonin modulates multiple calcium current subtypes in commissural interneurons of the neonatal mouse. J Neurophysiol 107:2212-9
Kadiri, Lolahon R; Kwan, Alex C; Webb, Watt W et al. (2011) Dopamine-induced oscillations of the pyloric pacemaker neuron rely on release of calcium from intracellular stores. J Neurophysiol 106:1288-98
Fergus, Daniel J; Decarvalho, Tagide N; Shaw, Kerry L (2011) Genetically regulated temporal variation of novel courtship elements in the Hawaiian cricket genus Laupala. Behav Genet 41:607-14

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