EXCEED THE SPACEPROVIDED. The goal of this training program isto recruit and educate physician-scientists who have the potential to become leaders in the field of Genetic Medicine. The program is designed to provide fellows with experience in all facets of modern medical genetics extending from the lab bench to the patient setting. The training experience emphasizes research in human genetics and prepares trainees for a career in academic medicine. Johns Hopkins has a long tradition of training post-doctoral fellows in human genetics. The origins of the postdoctoral training program can be traced to 1957 when Dr. Victor McKusick became the Director of the Moore Clinic. Under the direction of Dr. McKusick, this clinic became a 'home base' for medical genetics at Hopkins, and remained as such until 1989. Concurrently, a genetics training program in pediatrics was initiated under the direction of Dr. Barton Childs. The two programs werecombined in 1975. Funding for research fellows was provided by this training grant, which is currently in its twenty-fourth year. Expertise in medical and pediatric genetics illustrates a distinctive strength of the Hopkins program. Hopkins provides leadership in a number of areas of human genetics, particularly in the categorization and mapping of inherited traits, the study and management of patients with inborn errors of metabolism, the application of molecular and cellular genetic techniques to the understanding of disease, andthe diagnosis, classification andtreatment of disorders of connective tissue. In recognition of the growing importance of genetics in medicine, the Johns Hopkins University has formed and endowed the McKusick-Nathans Institute of Genetic Medicine. The Institute will coordinate clinical, educational and research activities in human genetics at the School of Medicine. This training program will benefit substantially from the environment and resources that will be provided by the Institute. The training program has an outstanding track record of educating physician-scientists who have made substantial contributions to human and medical genetics. To maintain the strong emphasis on research training and to accommodate recent changes in clinical training of geneticists, the duration and content of the program has been modified. Physicians desiring eligibility for the American Board of Medical Genetics Clinical Certification perform clinical duties for one year as a Genetics Resident. Stipend support during the year of residency is provided by the Institute of Genetic Medicine. Trainees then enter a two or three year program supported by this grant that provides an intensive in-depth experience in genetic research. Fellows not desiring Clinical Certification may enter the research program directly. Research is performed under the auspices of a carefully selected mentor, with additional mentoring and career guidance provided by the Program Director and Co-Director to facilitate transfer to a productive independent research career. PERFORMANCE SITE ========================================Section End===========================================
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