The Predoctoral Genetics Training Program (GTP) is an interdisciplinary program that provides enriched genetics education for students receiving their Ph.D. degrees in six departments: Biological Chemistry, Ecology and Evolutionary Biology (EEB), Human Genetics, Microbiology and Immunology, Molecular, Cellular and Developmental Biology (MCDB), and Pharmacology. Our goal is to train investigators who can apply disciplinary expertise to the new research opportunities of the post-genome-sequence era. The GTP includes 54 faculty members and 33 trainees. During the current funding period, 28 students received the Ph.D. degree, a new director was appointed, and the curriculum has been updated. Ongoing research projects range from microbial and viral gene regulation to yeast, plant, fly, mouse and human genetics, and functional genomics. Most students are supported for their second and third years of graduate study. Most of our graduates have gone on to productive research careers in academia and industry. Trainees benefit from a University environment that is strongly oriented towards graduate education, with a large and interactive research community that is among the top ten in NIH funding. University-supported core laboratory facilitate trainees' research by providing access to state-of-the-art technology including transgenic models, DNA sequencing, and large-scale gene expression. The curriculum includes formal coursework in genetics and interactive seminars. Each year, trainees select and host four outstanding geneticists from outside the University to lecture on an area of interest. The GTP is one of the oldest and largest NIH-supported training programs, and continues to be a vital component of graduate education and biomedical research at the University of Michigan.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007544-27
Application #
6755938
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Rhoades, Marcus M
Project Start
1978-07-01
Project End
2008-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
27
Fiscal Year
2004
Total Cost
$495,037
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Genetics
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Fitzsimmons, William J; Woods, Robert J; McCrone, John T et al. (2018) A speed-fidelity trade-off determines the mutation rate and virulence of an RNA virus. PLoS Biol 16:e2006459
Pérez Millán, María I; Vishnopolska, Sebastian A; Daly, Alexandre Z et al. (2018) Next generation sequencing panel based on single molecule molecular inversion probes for detecting genetic variants in children with hypopituitarism. Mol Genet Genomic Med :
Burby, Peter E; Simmons, Zackary W; Schroeder, Jeremy W et al. (2018) Discovery of a dual protease mechanism that promotes DNA damage checkpoint recovery. PLoS Genet 14:e1007512
Otero-Jiménez, Beatriz; Vandermeer, John H; Tucker, Priscilla K (2018) Effect of coffee agriculture management on the population structure of a forest dwelling rodent (Heteromys desmarestianus goldmani). Conserv Genet 19:495-499
Moccia, Amanda; Srivastava, Anshika; Skidmore, Jennifer M et al. (2018) Genetic analysis of CHARGE syndrome identifies overlapping molecular biology. Genet Med 20:1022-1029
Cloutier, Marissa; Harris, Clair; Gayen, Srimonta et al. (2018) Experimental Analysis of Imprinted Mouse X-Chromosome Inactivation. Methods Mol Biol 1861:177-203
Larson, Peter A; Moldovan, John B; Jasti, Naveen et al. (2018) Spliced integrated retrotransposed element (SpIRE) formation in the human genome. PLoS Biol 16:e2003067
Hernandez, Margarita R; Davis, Michael B; Jiang, Jianhao et al. (2018) Condensin I protects meiotic cohesin from WAPL-1 mediated removal. PLoS Genet 14:e1007382
Abbott, Jamie A; Meyer-Schuman, Rebecca; Lupo, Vincenzo et al. (2018) Substrate interaction defects in histidyl-tRNA synthetase linked to dominant axonal peripheral neuropathy. Hum Mutat 39:415-432
Li, Yilai; Schroeder, Jeremy W; Simmons, Lyle A et al. (2018) Visualizing bacterial DNA replication and repair with molecular resolution. Curr Opin Microbiol 43:38-45

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