The principal objective of our program is to train graduate students to function effectively as geneticists, enabling them to apply the rigor of genetic methods to pertinent issues in contemporary biology and medicine. The variety of approaches taken by the training faculty ensures a broad scope of training that encompasses microbial genetics, human and clinical genetics, yeast and plant geneticists, the developmental genetics of dipterans and nematodes, immunogenetics, aging, population genetics, as well as new directions in genomics. The predoctoral trainees supported by this program gain specific expertise from thesis research in one of these subdisciplines while gaining a broader intellectual outlook from formal coursework, first-year research rotations, and journal club. A well-established program of seminars and other forums for exchanges of research findings lends further perspective and provides valuable interaction with postdoctoral fellows, whose research training is also integrated into the program. Access to medical and clinical aspects of genetics derives both from formal coursework and from association with the Division of Medical Genetics in the Department of Medicine. A greater breadth of expertise is afforded the trainees by our affiliation with other units of the University, including the Departments of Botany and Zoology in the College of Arts and Sciences and the Departments of Biochemistry, Pathology, and Pediatrics in the School of Medicine, as well as with the Basic Sciences Division of the Fred Hutchinson Cancer Research Center.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
2T32GM007735-21
Application #
2800720
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Project Start
1979-07-01
Project End
2003-06-30
Budget Start
1999-07-01
Budget End
2000-06-30
Support Year
21
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Washington
Department
Genetics
Type
Schools of Arts and Sciences
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Queitsch, Christine; Carlson, Keisha D; Girirajan, Santhosh (2012) Lessons from model organisms: phenotypic robustness and missing heritability in complex disease. PLoS Genet 8:e1003041
Rohlfs, Rori V; Fullerton, Stephanie Malia; Weir, Bruce S (2012) Familial identification: population structure and relationship distinguishability. PLoS Genet 8:e1002469
Beutler, Lisa R; Eldred, Kiara C; Quintana, Albert et al. (2011) Severely impaired learning and altered neuronal morphology in mice lacking NMDA receptors in medium spiny neurons. PLoS One 6:e28168
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Clark, Nathaniel L; Gasper, Joe; Sekino, Masashi et al. (2009) Coevolution of interacting fertilization proteins. PLoS Genet 5:e1000570
Rohlfs, R V; Weir, B S (2008) Distributions of Hardy-Weinberg equilibrium test statistics. Genetics 180:1609-16
Clark, Nathaniel L; Findlay, Geoffrey D; Yi, Xianhua et al. (2007) Duplication and selection on abalone sperm lysin in an allopatric population. Mol Biol Evol 24:2081-90
Eklund, Jennifer L; Ulge, Umut Y; Eastberg, Jennifer et al. (2007) Altered target site specificity variants of the I-PpoI His-Cys box homing endonuclease. Nucleic Acids Res 35:5839-50
Klammer, Aaron A; MacCoss, Michael J (2006) Effects of modified digestion schemes on the identification of proteins from complex mixtures. J Proteome Res 5:695-700

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