Abstract

The goal of the Harvard M.D.-Ph.D. Program (Medical Scientist Training Program) is to train clinician-scientists who will be at the forefront of biomedical research and provide an interface between the most basic biomedical and technical research and its clinical application at the bedside. It is expected that these individuals will comprise a significant proportion of the future medical school faculties and will be able to address problems of disease etiology, pathophysiology and treatment at the most fundamental levels. These general goals are being pursued by selecting for our program the most research oriented and academically promising undergraduates and medical students who demonstrate a serious and long term commitment to academic careers in biomedical research. The M.D.-Ph.D. Program seeks to provide these students with the most thorough and up-to-date medical education and training for research careers in the laboratories and some of best investigators at Harvard and the Massachusetts Institute of Technology.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007753-23
Application #
6350995
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Shapiro, Bert I
Project Start
1979-07-01
Project End
2002-06-30
Budget Start
2001-07-01
Budget End
2002-06-30
Support Year
23
Fiscal Year
2001
Total Cost
$1,718,562
Indirect Cost

  Institution

Name
Harvard University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Hong, Xin; Sullivan, Ryan J; Kalinich, Mark et al. (2018) Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy. Proc Natl Acad Sci U S A 115:2467-2472
Katwa, Umakanth; D'Gama, Alissa M; Qualls, Anita E et al. (2018) Atypical presentations associated with non-polyalanine repeat PHOX2B mutations. Am J Med Genet A 176:1627-1631
McBrayer, Samuel K; Mayers, Jared R; DiNatale, Gabriel J et al. (2018) Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. Cell 175:101-116.e25
Steinhorn, Benjamin; Sorrentino, Andrea; Badole, Sachin et al. (2018) Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction. Nat Commun 9:4044
Giacomelli, Andrew O; Yang, Xiaoping; Lintner, Robert E et al. (2018) Mutational processes shape the landscape of TP53 mutations in human cancer. Nat Genet 50:1381-1387
Gurry, Thomas; HST Microbiome Consortium*; Gibbons, Sean M et al. (2018) Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort. Sci Rep 8:12699
Escudero, Silvia; Zaganjor, Elma; Lee, Susan et al. (2018) Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD. Mol Cell 69:729-743.e7
Bhan, Irun; Mosesso, Kelly; Goyal, Lipika et al. (2018) Detection and Analysis of Circulating Epithelial Cells in Liquid Biopsies From Patients With Liver Disease. Gastroenterology 155:2016-2018.e11
Sievers, Quinlan L; Gasser, Jessica A; Cowley, Glenn S et al. (2018) Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4CRBN activity. Blood 132:1293-1303
Rodin, Rachel E; Walsh, Christopher A (2018) Somatic Mutation in Pediatric Neurological Diseases. Pediatr Neurol 87:20-22

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