Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007775-08
Application #
3537891
Study Section
Pharmacology-Toxicology Review Committee (PTR)
Project Start
1979-07-01
Project End
1990-06-30
Budget Start
1987-07-01
Budget End
1988-06-30
Support Year
8
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Kansas Lawrence
Department
Type
Schools of Pharmacy
DUNS #
072933393
City
Lawrence
State
KS
Country
United States
Zip Code
66045
Reiff, Emily A; Nair, Sajiv K; Henri, John T et al. (2010) Total synthesis and evaluation of C26-hydroxyepothilone D derivatives for photoaffinity labeling of beta-tubulin. J Org Chem 75:86-94
Hutt, Oliver E; Inagaki, Jun; Reddy, Bollu S et al. (2009) Total synthesis and evaluation of 22-(3-azidobenzoyloxy)methyl epothilone C for photoaffinity labeling of beta-tubulin. Bioorg Med Chem Lett 19:3293-6
Desino, Kelly E; Ansar, Sabah; Georg, Gunda I et al. (2009) (3R,5S,7as)-(3,5-Bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a-yl)methanol, a novel neuroprotective agent. J Med Chem 52:7537-43
Grunewald, Gary L; Seim, Mitchell R; Regier, Rachel C et al. (2007) Exploring the active site of phenylethanolamine N-methyltransferase with 1,2,3,4-tetrahydrobenz[h]isoquinoline inhibitors. Bioorg Med Chem 15:1298-310
Hart, B W; Faiman, M D (1994) In vivo pharmacodynamic studies of the disulfiram metabolite S-methyl N,N-diethylthiolcarbamate sulfoxide: inhibition of liver aldehyde dehydrogenase. Alcohol Clin Exp Res 18:340-5
Hart, B W; Faiman, M D (1993) Bioactivation of S-methyl N,N-diethylthiolcarbamate to S-methyl N,N-diethylthiolcarbamate sulfoxide. Implications for the role of cytochrome P450. Biochem Pharmacol 46:2285-90
Hart, B W; Faiman, M D (1992) In vitro and in vivo inhibition of rat liver aldehyde dehydrogenase by S-methyl N,N-diethylthiolcarbamate sulfoxide, a new metabolite of disulfiram. Biochem Pharmacol 43:403-6
Yourick, J J; Faiman, M D (1991) Disulfiram metabolism as a requirement for the inhibition of rat liver mitochondrial low Km aldehyde dehydrogenase. Biochem Pharmacol 42:1361-6
Hart, B W; Yourick, J J; Faiman, M D (1990) S-methyl-N,N-diethylthiolcarbamate: a disulfiram metabolite and potent rat liver mitochondrial low Km aldehyde dehydrogenase inhibitor. Alcohol 7:165-9
Faiman, M D; Januszkiewicz, A J (1986) Pulmonary oxygen toxicity in the rat and the role of histamine. Biochem Pharmacol 35:3889-92

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