Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008283-03
Application #
3538397
Study Section
Special Emphasis Panel (SRC (01))
Project Start
1988-09-30
Project End
1993-06-30
Budget Start
1990-07-01
Budget End
1991-06-30
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
Yale University
Department
Type
Schools of Arts and Sciences
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520

  Publications

Buzovetsky, Olga; Tang, Chenxiang; Knecht, Kirsten M et al. (2018) The SAM domain of mouse SAMHD1 is critical for its activation and regulation. Nat Commun 9:411
Knecht, Kirsten M; Buzovetsky, Olga; Schneider, Constanze et al. (2018) The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1. Proc Natl Acad Sci U S A 115:E10022-E10031
Kostylev, Mikhail A; Tuttle, Marcus D; Lee, Suho et al. (2018) Liquid and Hydrogel Phases of PrPC Linked to Conformation Shifts and Triggered by Alzheimer's Amyloid-? Oligomers. Mol Cell 72:426-443.e12
Mentes, Ahmet; Huehn, Andrew; Liu, Xueqi et al. (2018) High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc Natl Acad Sci U S A 115:1292-1297
Kumar, Nikit; Leonzino, Marianna; Hancock-Cerutti, William et al. (2018) VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites. J Cell Biol 217:3625-3639
Sinclair, Julie K L; Walker, Allison S; Doerner, Amy E et al. (2018) Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR. Cell Chem Biol 25:857-870.e7
Chen, Shuliang; Bonifati, Serena; Qin, Zhihua et al. (2018) SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-?B and interferon pathways. Proc Natl Acad Sci U S A 115:E3798-E3807
Benedetti, Lorena; Barentine, Andrew E S; Messa, Mirko et al. (2018) Light-activated protein interaction with high spatial subcellular confinement. Proc Natl Acad Sci U S A 115:E2238-E2245
St Gelais, Corine; Kim, Sun Hee; Maksimova, Victoria V et al. (2018) A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation. J Virol 92:
Iwamoto, Daniel V; Huehn, Andrew; Simon, Bertrand et al. (2018) Structural basis of the filamin A actin-binding domain interaction with F-actin. Nat Struct Mol Biol 25:918-927

Showing the most recent 10 out of 116 publications