Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008319-05
Application #
2167915
Study Section
Cellular and Molecular Basis of Disease Review Committee (CMBD)
Project Start
1989-07-01
Project End
1994-06-30
Budget Start
1993-07-01
Budget End
1994-06-30
Support Year
5
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Rutgers University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
038633251
City
New Brunswick
State
NJ
Country
United States
Zip Code
08901
Balasubramanian, Sreekala; Xu, Fei; Olson, Wilma K (2009) DNA sequence-directed organization of chromatin: structure-based computational analysis of nucleosome-binding sequences. Biophys J 96:2245-60
Locasale, Jason W; Napoli, Andrew A; Chen, Shengfeng et al. (2009) Signatures of protein-DNA recognition in free DNA binding sites. J Mol Biol 386:1054-65
Barbieri, Christopher M; Kaul, Malvika; Pilch, Daniel S (2007) Use of 2-aminopurine as a fluorescent tool for characterizing antibiotic recognition of the bacterial rRNA A-site. Tetrahedron 63:3567-6574
Kaul, Malvika; Barbieri, Christopher M; Srinivasan, Annankoil R et al. (2007) Molecular determinants of antibiotic recognition and resistance by aminoglycoside phosphotransferase (3')-IIIa: a calorimetric and mutational analysis. J Mol Biol 369:142-56
Barbieri, Christopher M; Kaul, Malvika; Bozza-Hingos, Melanie et al. (2007) Defining the molecular forces that determine the impact of neomycin on bacterial protein synthesis: importance of the 2'-amino functionality. Antimicrob Agents Chemother 51:1760-9
Barbieri, Christopher M; Pilch, Daniel S (2006) Complete thermodynamic characterization of the multiple protonation equilibria of the aminoglycoside antibiotic paromomycin: a calorimetric and natural abundance 15N NMR study. Biophys J 90:1338-49
Hyde, Timothy J; Bryan, Michael A; Brodsky, Barbara et al. (2006) Sequence dependence of renucleation after a Gly mutation in model collagen peptides. J Biol Chem 281:36937-43
Togneri, John; Cheng, Yi-Shan; Munson, Mary et al. (2006) Specific SNARE complex binding mode of the Sec1/Munc-18 protein, Sec1p. Proc Natl Acad Sci U S A 103:17730-5
Toro-Roman, Alejandro; Mack, Timothy R; Stock, Ann M (2005) Structural analysis and solution studies of the activated regulatory domain of the response regulator ArcA: a symmetric dimer mediated by the alpha4-beta5-alpha5 face. J Mol Biol 349:11-26
Kaul, Malvika; Barbieri, Christopher M; Pilch, Daniel S (2005) Defining the basis for the specificity of aminoglycoside-rRNA recognition: a comparative study of drug binding to the A sites of Escherichia coli and human rRNA. J Mol Biol 346:119-34

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