Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008420-08
Application #
2872562
Study Section
Special Emphasis Panel (SRC (07))
Project Start
1991-07-01
Project End
2000-06-30
Budget Start
1999-07-01
Budget End
2000-06-30
Support Year
8
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Wayne State University
Department
Surgery
Type
Schools of Medicine
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Kovalenko, Pavlo L; Flanigan, Thomas L; Chaturvedi, Lakshmi et al. (2012) Influence of defunctionalization and mechanical forces on intestinal epithelial wound healing. Am J Physiol Gastrointest Liver Physiol 303:G1134-43
Gayer, Christopher P; Craig, David H; Flanigan, Thomas L et al. (2010) ERK regulates strain-induced migration and proliferation from different subcellular locations. J Cell Biochem 109:711-25
Gayer, Christopher P; Chaturvedi, Lakshmi S; Wang, Shouye et al. (2009) Delineating the signals by which repetitive deformation stimulates intestinal epithelial migration across fibronectin. Am J Physiol Gastrointest Liver Physiol 296:G876-85
Brown, Kristian L; Palyvoda, Olena Y; Thakur, Jagdish S et al. (2009) Differentiation of alloreactive versus CD3/CD28 stimulated T-lymphocytes using Raman spectroscopy: a greater specificity for noninvasive acute renal allograft rejection detection. Cytometry A 75:917-23
Flanigan, Thomas L; Craig, David H; Gayer, Christopher P et al. (2009) The effects of increased extracellular deformation, pressure, and integrin phosphorylation on fibroblast migration. J Surg Res 156:103-9
Gayer, Christopher P; Basson, Marc D (2009) The effects of mechanical forces on intestinal physiology and pathology. Cell Signal 21:1237-44
Chaturvedi, Lakshmi S; Saad, Samira A; Bakshi, Neil et al. (2009) Strain matrix-dependently dissociates gut epithelial spreading and motility. J Surg Res 156:217-23
Gayer, Christopher P; Chaturvedi, Lakshmi S; Wang, Shouye et al. (2009) Strain-induced proliferation requires the phosphatidylinositol 3-kinase/AKT/glycogen synthase kinase pathway. J Biol Chem 284:2001-11
Kwon, David S; Gao, Xiaohua; Liu, Yong Bo et al. (2008) Treatment with bone marrow-derived stromal cells accelerates wound healing in diabetic rats. Int Wound J 5:453-63
Flanigan, Thomas L; Owen, Cheri R; Gayer, Christopher et al. (2008) Supraphysiologic extracellular pressure inhibits intestinal epithelial wound healing independently of luminal nutrient flow. Am J Surg 196:683-9

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