Continuing funding is requested to support 9 predoctoral trainees of the Chemistry/Biology TrainingProgram, for the next five-years. The Training Program consists of 26 faculty members fromfourparticipating graduate units: Organic Division of the Chemistry Department, Biological Division ofthe Chemistry Department, Division of Medicinal Chemistry of the College of Pharmacy, and theOhio State Biochemistry Program (OSBP). The participating faculty members from OSBP areaffiliated with many departments and colleges. The research projects of the participating facultycover five broad areas: Area 1: Synthetic and Medicinal Chemistry; Area 2: Enzymology andBiosynthetic Pathways; Area 3: Protein Biochemistry and Engineering; Area 4: Structural Biology;and Area 5: Molecular and Cell Biology. The Chemistry/Biology Training Program is not a separategraduate program. Instead, students will be recruited into the four participating graduate programsand receive training at the chemistry/biology interface. Key elements of the training include monthlyluncheon seminars, annual symposium, regular seminars, and the requirement to cover bothchemistry and biology disciplines in lab rotations, course work, general exam proposals, anddissertation research. The Executive Committee will evaluate the progress of trainees annually forreappointment. Trainees will attend a workshop on Responsible Conduct of Research. Strong effortwill be devoted to recruiting and retention of underrepresented minority students. During the past 9years, 42 trainees have participated or are still participating in the program; many of the traineeshave also been supported by other fellowshipsfrom the university or other funding agencies. Fifteentrainees have successfully completed the training program and subsequently moved ontopermanent positions in academe, government, or industry or postdoctoral positions.
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