The University of North Carolina (UNC) Molecular and Cellular Biophysics Program (MCBP) is a highly successful interdisciplinary graduate training program with three essential goals: 1. To attract a diverse cohort of talented post-graduate students to apply the methods and concepts of the quantitative and mathematical sciences to problems in biology; 2. To provide a flexible vehicle for training this diverse group o graduate students who share with our biophysics faculty a commitment to developing molecular level descriptions of complex biological systems and processes; 3. To foster interactions and enhance the training and research environment within this diverse group of faculty and students. Having weathered State and Federal budget cuts as well as significant reorganization of graduate training in the biomedical sciences, the MCBP remains vibrant and central to the success of interdisciplinary biophysical research at UNC-Chapel Hill. The retiring Program Director has recruited as future Co-Directors two committed and energetic young faculty from participating departments located in UNC's two principle academic centers: School of Medicine & College of Arts and Sciences. They are ideally positioned to maintain the Program's rigor, adaptability, and visibility as well as to garner resources to guarantee its future success. This application is for continued funding of this successful training program in an area critical to biomedical research.
Biophysics is an interdisciplinary field of the biomedical sciences that aims to understand the mechanism of human health and disease on a molecular scale using the tools of the physical and quantitative sciences. The Molecular and Cellular Biophysics Program (MCBP) at the University of North Carolina at Chapel Hill is an established and highly successful training program in biophysics that seeks refunding in order to train students for this rapidly advancing and critical field.
| Hayne, Cassandra K; Yumerefendi, Hayretin; Cao, Lin et al. (2018) We FRET so You Don't Have To: New Models of the Lipoprotein Lipase Dimer. Biochemistry 57:241-254 |
| Guseman, Alex J; Perez Goncalves, Gerardo M; Speer, Shannon L et al. (2018) Protein shape modulates crowding effects. Proc Natl Acad Sci U S A 115:10965-10970 |
| Kudlacek, Stephan T; Premkumar, Lakshmanane; Metz, Stefan W et al. (2018) Physiological temperatures reduce dimerization of dengue and Zika virus recombinant envelope proteins. J Biol Chem 293:8922-8933 |
| Studer, Sabine; Hansen, Douglas A; Pianowski, Zbigniew L et al. (2018) Evolution of a highly active and enantiospecific metalloenzyme from short peptides. Science 362:1285-1288 |
| Pablo, Michael; Ramirez, Samuel A; Elston, Timothy C (2018) Particle-based simulations of polarity establishment reveal stochastic promotion of Turing pattern formation. PLoS Comput Biol 14:e1006016 |
| Guffy, Sharon L; Teets, Frank D; Langlois, Minnie I et al. (2018) Protocols for Requirement-Driven Protein Design in the Rosetta Modeling Program. J Chem Inf Model 58:895-901 |
| Adikes, Rebecca C; Hallett, Ryan A; Saway, Brian F et al. (2018) Control of microtubule dynamics using an optogenetic microtubule plus end-F-actin cross-linker. J Cell Biol 217:779-793 |
| Haase, Karen P; Fox, Jaime C; Byrnes, Amy E et al. (2018) Stu2 uses a 15-nm parallel coiled coil for kinetochore localization and concomitant regulation of the mitotic spindle. Mol Biol Cell 29:285-294 |
| Kirkpatrick, Christine L; Parsley, Nicole C; Bartges, Tessa E et al. (2018) Fungal Secretome Analysis via PepSAVI-MS: Identification of the Bioactive Peptide KP4 from Ustilago maydis. J Am Soc Mass Spectrom 29:859-865 |
| Jiang, Yuhang; Fay, James M; Poon, Chi-Duen et al. (2018) Nanoformulation of Brain-Derived Neurotrophic Factor with Target Receptor-Triggered-Release in the Central Nervous System. Adv Funct Mater 28: |
Showing the most recent 10 out of 96 publications
