Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007147-18
Application #
3540181
Study Section
Research Manpower Review Committee (MR)
Project Start
1990-07-01
Project End
1995-06-30
Budget Start
1992-07-01
Budget End
1993-06-30
Support Year
18
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Lavik, Andrew R; Zhong, Fei; Chang, Ming-Jin et al. (2015) A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2. Oncotarget 6:27388-402
Roth, Justin C; Alberti, Michael O; Ismail, Mourad et al. (2015) MGMT enrichment and second gene co-expression in hematopoietic progenitor cells using separate or dual-gene lentiviral vectors. Virus Res 196:170-80
Chang, Ming-Jin; Zhong, Fei; Lavik, Andrew R et al. (2014) Feedback regulation mediated by Bcl-2 and DARPP-32 regulates inositol 1,4,5-trisphosphate receptor phosphorylation and promotes cell survival. Proc Natl Acad Sci U S A 111:1186-91
Greenberg, Edward F; Lavik, Andrew R; Distelhorst, Clark W (2014) Bcl-2 regulation of the inositol 1,4,5-trisphosphate receptor and calcium signaling in normal and malignant lymphocytes: potential new target for cancer treatment. Biochim Biophys Acta 1843:2205-10
Allen, Kristi L; Fonseca, Fabio V; Betapudi, Venkaiah et al. (2012) A novel pathway for human endothelial cell activation by antiphospholipid/anti-ýý2 glycoprotein I antibodies. Blood 119:884-93
Grimberg, Brian T; Scheetz, Emily A; Erickson, John J et al. (2012) Increased reticulocyte count from cord blood samples using hypotonic lysis. Exp Parasitol 132:304-7
Zhong, Fei; Harr, Michael W; Bultynck, Geert et al. (2011) Induction of Ca²+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction. Blood 117:2924-34
Molitoris, Jason K; McColl, Karen S; Swerdlow, Sarah et al. (2011) Glucocorticoid elevation of dexamethasone-induced gene 2 (Dig2/RTP801/REDD1) protein mediates autophagy in lymphocytes. J Biol Chem 286:30181-9
Molitoris, Jason K; McColl, Karen S; Distelhorst, Clark W (2011) Glucocorticoid-mediated repression of the oncogenic microRNA cluster miR-17~92 contributes to the induction of Bim and initiation of apoptosis. Mol Endocrinol 25:409-20
Allen, Kristi L; Hamik, Anne; Jain, Mukesh K et al. (2011) Endothelial cell activation by antiphospholipid antibodies is modulated by Kruppel-like transcription factors. Blood 117:6383-91

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