The Cardiovascular Research Training Program at Brigham and Women's Hospital aims to prepare trainees for independent careers in investigative pursuits. The three themes of particular focus for this T-32 program include 1) Myocardial Cellular and Molecular Biology and Genetics, 2) Vascular Cell and Molecular Biology, and 3) Translational/Clinical Cardiovascular Research. We propose to strive to continue our record of preparing our trainees to develop independent research programs, obtain faculty positions, and acquire peer-reviewed funding. Our environment offers substantial resources to trainees, ranging from core laboratories within Brigham and Women's Hospital, formal educational opportunities including those of the adjacent Harvard School of Public Health, and ample resources within the individual laboratories of faculty members. The program provides a structured program for each trainee including formulating formal Individual Development Plans for each trainee, orientation lectures, formal instruction in responsible conduct and professionalism in research, advanced course work, multiple inter-disciplinary research group meetings and seminar series, and tailored and flexible research experiences. Indeed, a historical strength of our T-32 program is working with trainees to place them in the best laboratory and mentoring environment to meet their individual training needs and career goals whether it be at BWH and its partner institution the MGH, or in the broader surrounding environment including the Dana-Farber Cancer Institute, the Harvard Medical School and School of Public Health, Children's Hospital, MIT, the Harvard BioLabs and Stem Cell Regenerative Biology Institute, and the Broad Institute among others. Each trainee works under the close supervision of a faculty mentor throughout their training. In addition, a Fellowship Advisory Board oversees the program and monitors closely the progress of trainees and their Individual Development Plans. The Research-in-Progress seminar, an annual Fellow's Poster Session, and Cardiovascular Grand Rounds serve to highlight and support the work of the post-doctoral trainees. We have a particular and successful commitment to recruiting and fostering the careers of woman and minority trainees. In this renewal application we propose to continue our longstanding record (documented within) of preparing a talented pool of fellows for successful academic careers.

Public Health Relevance

The Cardiovascular Research Training Program at Brigham and Women's Hospital aims to prepare trainees for independent careers in investigative pursuits. Focus areas of this T-32 include 1) Myocardial Cellular and Molecular Biology and Genetics, 2) Vascular Cell and Molecular Biology, and 3) Translational/Clinical Cardiovascular Research. Our environment offers substantial resources to trainees to ensure continuation of our longstanding record of preparing a talented pool of trainees for productive research careers.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007604-34
Application #
9486963
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Wang, Wayne C
Project Start
1985-07-01
Project End
2020-06-30
Budget Start
2018-07-01
Budget End
2019-06-30
Support Year
34
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
Greene, Stephen J; Vaduganathan, Muthiah; Khan, Muhammad Shahzeb et al. (2018) Prevalent and Incident Heart Failure in Cardiovascular Outcome Trials of Patients With Type 2 Diabetes. J Am Coll Cardiol 71:1379-1390
Singh, Avinainder; Collins, Bradley L; Gupta, Ankur et al. (2018) Cardiovascular Risk and Statin Eligibility of Young Adults After an MI: Partners YOUNG-MI Registry. J Am Coll Cardiol 71:292-302
Restrepo, Daniel; Vaduganathan, Muthiah; Fenves, Andrew Z (2018) Uremic Pericarditis: Distinguishing Features in a Now-Uncommon Clinical Syndrome. South Med J 111:754-757
Patel, Ravi B; Vaduganathan, Muthiah; Greene, Stephen J et al. (2018) Nomenclature in heart failure: a call for objective, reproducible, and biologically-driven terminology. Eur J Heart Fail 20:1379-1381
Wadhera, Rishi K; Joynt Maddox, Karen E; Wang, Yun et al. (2018) Association Between 30-Day Episode Payments and Acute Myocardial Infarction Outcomes Among Medicare Beneficiaries. Circ Cardiovasc Qual Outcomes 11:e004397
Wadhera, Rishi K; Joynt Maddox, Karen E; Yeh, Robert W et al. (2018) Public Reporting of Percutaneous Coronary Intervention Outcomes: Moving Beyond the Status Quo. JAMA Cardiol 3:635-640
Wadhera, Rishi K; Joynt Maddox, Karen E; Wang, Yun et al. (2018) 30-Day Episode Payments and Heart Failure Outcomes Among Medicare Beneficiaries. JACC Heart Fail 6:379-387
Kim, Han Na; Fesseha, Betiel; Anzaldi, Laura et al. (2018) Antibody-Mediated Extreme Insulin Resistance: A Report of Three Cases. Am J Med 131:102-106
Vijayakumar, Shilpa; Vaduganathan, Muthiah; Butler, Javed (2018) Glucose-Lowering Therapies and Heart Failure in Type 2 Diabetes Mellitus: Mechanistic Links, Clinical Data, and Future Directions. Circulation 137:1060-1073
Wadhera, Rishi K; Joynt Maddox, Karen E; Fonarow, Gregg C et al. (2018) Association of the Affordable Care Act's Medicaid Expansion With Care Quality and Outcomes for Low-Income Patients Hospitalized With Heart Failure. Circ Cardiovasc Qual Outcomes 11:e004729

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