This proposal describes an interdisciplinary training program in Cardiovascular Biomedical Engineering dedicated to training predoctoral students. Students will receive a multidisciplinary education in the biological and engineering disciplines focusing on cardiovascular health. A major goal of this program is to meet the demands of a growing biomedical engineering field and interdisciplinary workforce. This program takes advantage of the strong expertise in bioengineering and cardiovascular biology present at the University of Arizona. Areas of expertise include: biomechanics, biomaterials, optics, molecular genetics, vascular physiology, radiology, imaging, tissue engineering, genetic engineering, and biocomputing. Training faculty are independent researchers with a shared commitment to graduate training. The faculty have a strong record of support and are actively involved in collaborative research activities. Clinical and industrial experiences will foster the development of translational research projects for trainees. Training within this program involves laboratory and didactic experience. The didactic component includes the core biomedical engineering graduate curriculum, the availability of numerous elective graduate courses and regularly scheduled forums and seminars. Students participate in informal discussion groups and have multiple opportunities to present their research in oral and poster form. Progress of the trainees is monitored by the trainee's mentor, their respective graduate program, a training grant program committee, and an advisory board. Students perform research rotations and projects in participating laboratories that are focused on: microvascular engineering, vascular biomechanics, vascular modeling, optical vascular imaging, ultrasound and magnetic resonance imaging of vascular perfusion, cardiovascular instrumentation, cardiovascular devices, cardiac electrophysiology, vascular genomics and molecular diagnostics of vascular tissues. This is a resubmission of a renewal application;graduates of this training program from the last 10 years are now engaged in post-doctoral training and have taken positions of leadership in the biomedical industry.

Public Health Relevance

Cardiovascular biomedical engineers create the medical technology used in the diagnosis and treatment of cardiovascular disease. Continued advancement in this complex field requires students with unique didactic and laboratory training. In the Cardiovascular Biomedical Engineering Training Program, students receive the basic and advanced coursework, laboratory training, and skill development necessary to develop cutting-edge diagnostic equipment, pharmacological agents, and medical devices directed at the cardiovascular system.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007955-14
Application #
8680297
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Carlson, Drew E
Project Start
2000-04-01
Project End
2016-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
14
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Arizona
Department
Biomedical Engineering
Type
Biomed Engr/Col Engr/Engr Sta
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Garlant, Jacob A; Ammann, Kaitlyn R; Slepian, Marvin J (2018) Stretchable Electronic Wearable Motion Sensors Delineate Signatures of Human Motion Tasks. ASAIO J 64:351-359
Lindeman, Leila R; Randtke, Edward A; High, Rachel A et al. (2018) A comparison of exogenous and endogenous CEST MRI methods for evaluating in vivo pH. Magn Reson Med 79:2766-2772
Jones, Kyle M; Pollard, Alyssa C; Pagel, Mark D (2018) Clinical applications of chemical exchange saturation transfer (CEST) MRI. J Magn Reson Imaging 47:11-27
Jones, Kyle M; Pagel, Mark D; Cárdenas-Rodríguez, Julio (2018) Linearization improves the repeatability of quantitative dynamic contrast-enhanced MRI. Magn Reson Imaging 47:16-24
Ulep, Tiffany-Heather; Yoon, Jeong-Yeol (2018) Challenges in paper-based fluorogenic optical sensing with smartphones. Nano Converg 5:14
Solnes, Lilja B; Jones, Krystyna M; Rowe, Steven P et al. (2017) Diagnostic Value of 18F-FDG PET/CT Versus MRI in the Setting of Antibody-Specific Autoimmune Encephalitis. J Nucl Med 58:1307-1313
Welge, Weston A; Barton, Jennifer K (2017) In vivo endoscopic Doppler optical coherence tomography imaging of the colon. Lasers Surg Med 49:249-257
Rosado-Toro, Jose A; Abidov, Aiden; Altbach, Maria I et al. (2017) Segmentation of the right ventricle in four chamber cine cardiac MR images using polar dynamic programming. Comput Med Imaging Graph 62:15-25
Jones, Kyle M; Randtke, Edward A; Yoshimaru, Eriko S et al. (2017) Clinical Translation of Tumor Acidosis Measurements with AcidoCEST MRI. Mol Imaging Biol 19:617-625
Crosby, Jessica R; DeCook, Katrina J; Tran, Phat L et al. (2017) A Physical Heart Failure Simulation System Utilizing the Total Artificial Heart and Modified Donovan Mock Circulation. Artif Organs 41:E52-E65

Showing the most recent 10 out of 73 publications