The Comparative Medical Science Training Program endeavors to provide graduate veterinarians with scientific, communicative, and inter-professional skills to become independent research scientists and scientists who contribute to interdisciplinary biomedical research. In addition to providing rigorous research training, the training program emphasizes the role of research veterinarians as part of the larger comparative medicine community, which includes MD scientists, PhD scientists, laboratory animal clinicians and pathologists (both MD and DVM) in order to foster an appreciation for the full spectrum of clinical- and research-oriented individuals in biomedical research. Biomedical research is increasingly inter-disciplinary, and veterinarians trained in comparative medical research must not only be proficient in their individual research areas, but also provide expertise in animal modeling, such as mouse biology. The national shortage of veterinarians contributing to biomedical research has been documented by the National Academies. The National Center for Research Resources, NIH, has placed research training of veterinarians as a high program priority in order to address this deficiency. Veterinarians are well-suited for biomedical research because of their comparative medical training, their expertise in laboratory animals, and their talent for animal modeling of human disease. This training program will take place within the Center for Comparative Medicine, a highly productive research center that is co-sponsored by the Schools of Medicine and Veterinary Medicine at the University of California at Davis. The Center houses MD, MD/PhD, DVM/PhD and PhD research scientists with a broad array of expertise who investigate animal models of human disease, including infectious diseases, cancer, mouse biology, and genomics. Center faculty interface with a number of closely linked programs and centers that contribute to the training environment, including the Mouse Biology Program, the California National Primate Research Center, the Center for Laboratory Animal Science, the University of California Davis Medical Center, and the Cancer Center. Faculty within the Center for Comparative Medicine as well as faculty in other linked programs will provide the mentoring for students, thereby providing maximal opportunity to match students with their areas of interest.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Institutional National Research Service Award (T32)
Project #
5T32RR007038-22
Application #
7650412
Study Section
Special Emphasis Panel (ZRR1-CM-6 (01))
Program Officer
Watson, William T
Project Start
1988-07-01
Project End
2011-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
22
Fiscal Year
2009
Total Cost
$400,312
Indirect Cost
Name
University of California Davis
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Carlson-Bremer, Daphne; Colegrove, Kathleen M; Gulland, Frances M D et al. (2015) Epidemiology and pathology of Toxoplasma gondii in free-ranging California sea lions (Zalophus californianus). J Wildl Dis 51:362-73
Luff, Jennifer A; Yuan, Hang; Kennedy, Douglas et al. (2014) Keratinocyte antiviral response to Poly(dA:dT) stimulation and papillomavirus infection in a canine model of X-linked severe combined immunodeficiency. PLoS One 9:e102033
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Fritz, Heather M; Buchholz, Kerry R; Chen, Xiucui et al. (2012) Transcriptomic analysis of toxoplasma development reveals many novel functions and structures specific to sporozoites and oocysts. PLoS One 7:e29998
Fritz, Heather M; Bowyer, Paul W; Bogyo, Matthew et al. (2012) Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance. PLoS One 7:e29955
Kelly, Kristi R; Kapatkin, Amy R; Zwingenberger, Allison L et al. (2012) Efficacy of antibiotic-impregnated polymethylmethacrylate beads in a rhesus macaque (Macaca mulatta) with osteomyelitis. Comp Med 62:311-5
Fritz, H; Barr, B; Packham, A et al. (2012) Methods to produce and safely work with large numbers of Toxoplasma gondii oocysts and bradyzoite cysts. J Microbiol Methods 88:47-52
Carlson-Bremer, Daphne; Johnson, Christine K; Miller, Robin H et al. (2012) Identification of two novel coccidian species shed by California sea lions (Zalophus californianus). J Parasitol 98:347-54

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