The major goal of this Program is to develop a new generation of physician-scientists. In order to accomplish this goal, selected medical students will gain a positive, comprehensive experience in biomedical research. They will (1) develop written proposals under the supervision of well-funded faculty preceptors, (2) conduct their projects in established and productive laboratories for 2-3 months during option periods, usually between their first year and second years of medical school, (3) report their results in oral and written form, and (4) participate in research-related activities, i.e. seminars. These experiences will increase their interest in and awareness of careers in academic medicine. Twenty-four training positions will be offered each year. With the guidance of faculty research mentors, students will develop 4-5 page proposals that are goal-oriented, achievable, and include a hypothesis, literature review, and methodology. Proposals will be selected by peer review based on the quality of the proposal, productivity of the mentor, and training environment. At the end of the project, a final written report is required. Other Program enhancements include a dedicated seminar series, special lectures, and opportunities to present and publish the work. Special efforts will continue to be made to attract ethnic minority individuals. A wide variety of funded scientific programs are included in order to accommodate a broad range of medical student interests. Research projects will be available in (1) Endocrinology and Metabolism, (2) Molecular Biology, (3) Physiology and Biophysics, (4) Cardiovascular Diseases, (5) Connective Tissue Diseases, (6) Infectious Disease and Immunology, (7) Cancer, (8) Neurosciences, (9) Visual System, and (10) Preventive Medicine. Fifty-five faculty members, holding over $32.5 million in annual grant awards and $33.0 million in pending grants, are available as research preceptors. Additional faculty members who meet these high standards will be included as preceptors in the future.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
NRSA Short -Term Research Training (T35)
Project #
2T35DK007405-21
Application #
6845022
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Podskalny, Judith M,
Project Start
1980-06-01
Project End
2010-05-31
Budget Start
2005-06-01
Budget End
2006-05-31
Support Year
21
Fiscal Year
2005
Total Cost
$149,422
Indirect Cost
Name
University of Tennessee Health Science Center
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163
Henderson, DeAnna; Frieson, Danielle; Zuber, Jeffrey et al. (2017) Metformin Has Positive Therapeutic Effects in Colon Cancer and Lung Cancer. Am J Med Sci 354:246-251
Stentz, Frankie B; Brewer, Amy; Wan, Jim et al. (2016) Remission of pre-diabetes to normal glucose tolerance in obese adults with high protein versus high carbohydrate diet: randomized control trial. BMJ Open Diabetes Res Care 4:e000258
Kansal, Rita G; McCravy, Matthew S; Basham, Jacob H et al. (2016) Inhibition of melanocortin 1 receptor slows melanoma growth, reduces tumor heterogeneity and increases survival. Oncotarget 7:26331-45
Chong, R William; Vasudevan, Vijaya; Zuber, Jeffrey et al. (2016) Metformin Has a Positive Therapeutic Effect on Prostate Cancer in Patients With Type 2 Diabetes Mellitus. Am J Med Sci 351:416-9
Bulger, David A; Conley, Jermaine; Conner, Spencer H et al. (2015) Role of PTEN in TNF? induced insulin resistance. Biochem Biophys Res Commun 461:533-6
Dale, James B; Niedermeyer, Shannon E; Agbaosi, Tina et al. (2015) Protective immunogenicity of group A streptococcal M-related proteins. Clin Vaccine Immunol 22:344-50
Hagopian, William; Ferry Jr, Robert J; Sherry, Nicole et al. (2013) Teplizumab preserves C-peptide in recent-onset type 1 diabetes: two-year results from the randomized, placebo-controlled Protégé trial. Diabetes 62:3901-8
Herr, Michael J; Kotha, Jayaprakash; Hagedorn, Nikolaus et al. (2013) Tetraspanin CD9 promotes the invasive phenotype of human fibrosarcoma cells via upregulation of matrix metalloproteinase-9. PLoS One 8:e67766
Levin, Michael C; Lee, Sangmin; Gardner, Lidia A et al. (2013) Autoantibodies to Non-myelin Antigens as Contributors to the Pathogenesis of Multiple Sclerosis. J Clin Cell Immunol 4:
Siddiqi, Shahzad; Sheth, Atur; Patel, Feenalie et al. (2013) Intestinal caveolin-1 is important for dietary fatty acid absorption. Biochim Biophys Acta 1831:1311-21

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