The San Diego State University-Minority Health and Health Disparity (SDSU-MHIRT) program will continue in the vein of the previous SDSU Minority International Training Program which is to encourage and support students from health disparity backgrounds who engage in an international biomedical research experience to pursue careers in the fields of basic science, biomedical, clinical and behavioral health and to increase the number of persons from health disparity populations who enter the field of biomedicine. Twelve trainees will have the opportunities to perform research in six areas encompassing public health and immigrant health, behavioral science, molecular biology/ethno-pharmacology; drug design and antibiotics; AIDS and Tuberculosis; hypertension; obesity and diabetes. Each research topic has been assigned to a geographical area supervised by the regional coordinator. Each foreign site is required to have adequate equipment for the execution of the MHIRT's students research proposal. In addition, mentorship will be provided at the international site either by the foreign mentor or a U.S. mentor. Sites and mentors have been designated based on their past track record of providing a sound research experience. Unique to this proposal is the fact that the MHIRT students will have an extended support system once they return to SDSU. The student based international research experience is part of an integrated approach in which other programs (MBRS, McNair, MARC, PREP) continue to support the students. Major sites are in Australia, Mexico, Peru, Ghana, Uganda, Spain and Italy. Of these, sites in Australia, Mexico, Ghana and Uganda have been very productive. Spain, Italy and a Mexico site in Tijuana have been added due to the research areas as well as a potential back-up in case of international problems. The last four years of the program have produced eleven students pursuing a Ph.D. in areas ranging from mathematics, organic chemistry, psychology and molecular biology with an additional four students applying to Ph.D. programs. Two students have received their Ph.D. and one is an assistant professor on a tenure track. Thirty six percent of the returning SDSU MIRT students were supported by other student programs. An Advisory Committee composed of research mentors and administrators will advise the Program Director concerning the execution of the grant, which emphasizes student mastery of biomedical research. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Minority International Research Training Grants (FIC) (T37)
Project #
5T37MD001442-11
Application #
7447312
Study Section
Special Emphasis Panel (ZMD1-LW (01))
Program Officer
Nettey, Robert
Project Start
1995-09-30
Project End
2009-06-30
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
11
Fiscal Year
2008
Total Cost
$236,652
Indirect Cost
Name
San Diego State University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
073371346
City
San Diego
State
CA
Country
United States
Zip Code
92182
McConnell, Jeanette R; Alexander, Leslie A; McAlpine, Shelli R (2014) A heat shock protein 90 inhibitor that modulates the immunophilins and regulates hormone receptors without inducing the heat shock response. Bioorg Med Chem Lett 24:661-6
McConnell, Jeanette R; McAlpine, Shelli R (2013) Heat shock proteins 27, 40, and 70 as combinational and dual therapeutic cancer targets. Bioorg Med Chem Lett 23:1923-8
Kim, Seong Jong; Ramsey, Deborah M; Boyer, Cyrille et al. (2013) Effectively delivering a unique hsp90 inhibitor using star polymers. ACS Med Chem Lett 4:
McConnell, Jeanette R; Rananaware, Dimple P; Ramsey, Deborah M et al. (2013) A potential rhodium cancer therapy: studies of a cytotoxic organorhodium(I) complex that binds DNA. Bioorg Med Chem Lett 23:2527-31
Kim, Seong Jong; Lin, Chun Chieh; Pan, Chung-Mao et al. (2013) A structure-activity relationship study on multi-heterocyclic molecules: two linked thiazoles are required for cytotoxic activity. Medchemcomm 4:406-410
Ramsey, Deborah M; McConnell, Jeanette R; Alexander, Leslie D et al. (2012) An Hsp90 modulator that exhibits a unique mechanistic profile. Bioorg Med Chem Lett 22:3287-90
Antonio, Tiago; Koller, Silvia H; Hokoda, Audrey (2012) Peer influences on the dating aggression process among Brazilian street youth: a brief report. J Interpers Violence 27:1579-92
Davis, Melinda R; Singh, Erinprit K; Wahyudi, Hendra et al. (2012) Synthesis of sansalvamide A peptidomimetics: triazole, oxazole, thiazole, and pseudoproline containing compounds. Tetrahedron 68:1029-1051
Pan, Chung-Mao; Lin, Chun-Chieh; Kim, Seong Jong et al. (2012) Progress towards the synthesis of Urukthapelstatin A and two analogues. Tetrahedron Lett 53:4065-4069
Bussmann, R W; Malca, G; Glenn, A et al. (2011) Toxicity of medicinal plants used in traditional medicine in Northern Peru. J Ethnopharmacol 137:121-40

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