Abstract

The CERAD Clinical Task Force was established to develop a clinical assessment battery for the diagnosis and characterization of Alzheimer's disease (AD) and to standardize its administration and interpretation. In this revised application, the Task Force builds on the successful achievement of its original mission. Using unique resources developed through experience in standardizing criteria and assessment tools for probable AD across multiple centers, CERAD will continue to obtain follow- up studies of identically diagnosed and assessed subjects for longitudinal study until autopsy to determine clinical, neuropsychological, and neuropathologic findings. The data obtained will be used to examine already identified features of AD such as extrapyramidal dysfunction, and will permit examination of clinico-pathologic correlates of AD.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project--Cooperative Agreements (U01)
Project #
2U01AG006790-09A1
Application #
3726363
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
9
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Duke University
Department
Type
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705

  Publications

Fillenbaum, Gerda G; Burchett, Bruce M; Unverzagt, Frederick W et al. (2011) Norms for CERAD constructional praxis recall. Clin Neuropsychol 25:1345-58
Fillenbaum, Gerda G; van Belle, Gerald; Morris, John C et al. (2008) Consortium to Establish a Registry for Alzheimer's Disease (CERAD): the first twenty years. Alzheimers Dement 4:96-109
Klatte, Emily T; Scharre, Douglas W; Nagaraja, Haikady N et al. (2003) Combination therapy of donepezil and vitamin E in Alzheimer disease. Alzheimer Dis Assoc Disord 17:113-6
Taylor Jr, Donald H; Fillenbaum, Gerda G; Ezell, Michael E (2002) The accuracy of medicare claims data in identifying Alzheimer's disease. J Clin Epidemiol 55:929-37
Fillenbaum, G; Heyman, A; Peterson, B L et al. (2001) Use and cost of outpatient visits of AD patients: CERAD XXII. Neurology 56:1706-11
Fillenbaum, G; Heyman, A; Peterson, B L et al. (2001) Use and cost of hospitalization of patients with AD by stage and living arrangement: CERAD XXI. Neurology 56:201-6
Fillenbaum, G; Heyman, A; Peterson, B et al. (2000) Frequency and duration of hospitalization of patients with AD based on Medicare data: CERAD XX. Neurology 54:740-3
Clark, C M; Sheppard, L; Fillenbaum, G G et al. (1999) Variability in annual Mini-Mental State Examination score in patients with probable Alzheimer disease: a clinical perspective of data from the Consortium to Establish a Registry for Alzheimer's Disease. Arch Neurol 56:857-62
Heyman, A; Fillenbaum, G G; Gearing, M et al. (1999) Comparison of Lewy body variant of Alzheimer's disease with pure Alzheimer's disease: Consortium to Establish a Registry for Alzheimer's Disease, Part XIX. Neurology 52:1839-44
Koss, E; Peterson, B; Fillenbaum, G G (1999) Determinants of attrition in a natural history study of Alzheimer disease. Alzheimer Dis Assoc Disord 13:209-15

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