The study of Women's Health Across the Nation (SWAN I) was funded on September 1994 by the National Institutes on Aging in response to RFA AG-94-002 entitled """"""""Menopause and Health in Aging Women."""""""" The RFA identified four primary objectives and called for a Coordinating Center, Clinical Sites and a central endocrinology laboratory. This Coordinating Center application is a component of a set of applications, including seven clinic sites and central endocrinology laboratory, to continue SWAN for an additional five years. SWAN II proposes to continue the science begun under the current awards, building on the experience gained to further enhance the scientific contribution of the study to our knowledge of the role of menopause and aging on health in mid-aged and older women. To facilitate addressing the scientific goals of this renewal, the Coordinating Center (CC) will meet the following four goals. 1. The CC will maintain and continue to enhance the current distributed data management system (DMS) to collect, integrate, quality control and document for analysis data collected directly from the clinic sites and from the central laboratories. 2. The CC will continue to support the development and implementation of all core and sub-core SWAN protocols, including scientific input, forms design, manuals of operation, training and certification of site staff and on-going quality control and standardization of measurement through site visits, regular conference calls and review of data. 3. The CC will continue to provide, in collaboration with site statisticians, statistical experience in study design and analytic approach, coordinate the development of and maintain all analytic data sets and complete analyses for manuscripts and presentations. Administratively, the CC will continue to coordinate and support the SWAN administrative structure through conference call and meeting support, and by maintaining Steering Committee (SC) and Executive Committee (EC) minutes, assisting with Advisory Panel (AP) minutes, maintaining the study directory, committee lists and the SWAN Web Site. The CC will also maintain all study protocol documentation.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01AG012553-09
Application #
6475603
Study Section
Special Emphasis Panel (ZAG1-BJB-8 (O8))
Program Officer
Sherman, Sherry
Project Start
1994-09-30
Project End
2002-11-30
Budget Start
2002-02-01
Budget End
2002-11-30
Support Year
9
Fiscal Year
2002
Total Cost
$162,480
Indirect Cost
Name
New England Research Institute
Department
Type
DUNS #
153914080
City
Watertown
State
MA
Country
United States
Zip Code
02472
Crawford, Sybil L; Crandall, Carolyn J; Derby, Carol A et al. (2018) Menopausal hormone therapy trends before versus after 2002: impact of the Women's Health Initiative Study Results. Menopause :
Karlamangla, Arun S; Burnett-Bowie, Sherri-Ann M; Crandall, Carolyn J (2018) Bone Health During the Menopause Transition and Beyond. Obstet Gynecol Clin North Am 45:695-708
Beatty Moody, Danielle L; Chang, Yuefang; Brown, Charlotte et al. (2018) Everyday Discrimination and Metabolic Syndrome Incidence in a Racially/Ethnically Diverse Sample: Study of Women's Health Across the Nation. Psychosom Med 80:114-121
Duan, Chunzhe; Talbott, Evelyn; Brooks, Maria et al. (2018) Five-year exposure to PM2.5 and ozone and subclinical atherosclerosis in late midlife women: The Study of Women's Health Across the Nation. Int J Hyg Environ Health :
Yoshida, Kazuki; Yu, Zhi; Greendale, Gail A et al. (2018) Effects of analgesics on bone mineral density: A longitudinal analysis of the prospective SWAN cohort with three-group matching weights. Pharmacoepidemiol Drug Saf 27:182-190
Waetjen, L Elaine; Xing, Guibo; Johnson, Wesley O et al. (2018) Factors associated with reasons incontinent midlife women report for not seeking urinary incontinence treatment over 9 years across the menopausal transition. Menopause 25:29-37
Allshouse, Amanda A; Santoro, Nanette; Green, Robin et al. (2018) Religiosity and faith in relation to time to metabolic syndrome for Hispanic women in a multiethnic cohort of women-Findings from the Study of Women's Health Across the Nation (SWAN). Maturitas 112:18-23
Allshouse, Amanda; Pavlovic, Jelena; Santoro, Nanette (2018) Menstrual Cycle Hormone Changes Associated with Reproductive Aging and How They May Relate to Symptoms. Obstet Gynecol Clin North Am 45:613-628
Hanley, Carrie; Shields, Kelly J; Matthews, Karen A et al. (2018) Associations of cardiovascular fat radiodensity and vascular calcification in midlife women: The SWAN cardiovascular fat ancillary study. Atherosclerosis 279:114-121
Chyu, Laura; Upchurch, Dawn M (2018) A Longitudinal Analysis of Allostatic Load among a Multi-Ethnic Sample of Midlife Women: Findings from the Study of Women's Health Across the Nation. Womens Health Issues 28:258-266

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