Project Start
1986-09-30
Project End
1989-08-31
Budget Start
1987-09-01
Budget End
1988-08-31
Support Year
2
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Worcester Foundation for Biomedical Research
Department
Type
DUNS #
City
Shrewsbury
State
MA
Country
United States
Zip Code
01545
Nelson, J S; Giver, L; Ellington, A D et al. (1996) Incorporation of a non-nucleotide bridge into hairpin oligonucleotides capable of high-affinity binding to the Rev protein of HIV-1. Biochemistry 35:5339-44
Gryaznov, S M; Schultz, R; Chaturvedi, S K et al. (1994) Enhancement of selectivity in recognition of nucleic acids via chemical autoligation. Nucleic Acids Res 22:2366-9
Temsamani, J; Metelev, V; Levina, A et al. (1994) Inhibition of in vitro transcription by oligodeoxynucleotides. Antisense Res Dev 4:279-84
Zamecnik, P; Aghajanian, J; Zamecnik, M et al. (1994) Electron micrographic studies of transport of oligodeoxynucleotides across eukaryotic cell membranes. Proc Natl Acad Sci U S A 91:3156-60
Herrlein, M K; Letsinger, R L (1994) Selective chemical autoligation on a double-stranded DNA template. Nucleic Acids Res 22:5076-8
Goodchild, J (1992) Enhancement of ribozyme catalytic activity by a contiguous oligodeoxynucleotide (facilitator) and by 2'-O-methylation. Nucleic Acids Res 20:4607-12
Agrawal, S (1992) Antisense oligonucleotides as antiviral agents. Trends Biotechnol 10:152-8
Metelev, V; Agrawal, S (1992) Ion-exchange high-performance liquid chromatography analysis of oligodeoxyribonucleotide phosphorothioates. Anal Biochem 200:342-6
Rapaport, E; Misiura, K; Agrawal, S et al. (1992) Antimalarial activities of oligodeoxynucleotide phosphorothioates in chloroquine-resistant Plasmodium falciparum. Proc Natl Acad Sci U S A 89:8577-80
Goodchild, J; Kim, B; Zamecnik, P C (1991) The clearance and degradation of oligodeoxynucleotides following intravenous injection into rabbits. Antisense Res Dev 1:153-60

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