Abstract

The State University of New York Health Science Center at Brooklyn (SUNY-HSCB), in collaboration with the five other WIHS sites, has successfully responded to the evolving epidemic of HIV infection among women by rapidly establishing research protocols, developing and piloting instruments and recruiting a national cohort highly representative of the population of HIV infected women in this country. The SUNY cohort reached, and surpassed, its original recruitment goal in June 1995 and currently has 398 women entered (311 seropositive; 87 seronegative). As of visit three our loss to follow-up rate was only 5.1 percent (4.2 percent for the seropositive cohort). We are now proposing to combine continued follow-up of this cohort with new scientific investigations and comprehensive, detailed analyses. These analyses will bring state of the art technologies to bear on a cohort which reflects the current """"""""face"""""""" of the HIV epidemic, an epidemic which has changed in three basic ways in the decade since the first AIDS cohorts were assembled - gender, risk groups and therapeutic interventions. Our cohort is positioned to address the emerging scientific questions which those changes will engender.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01AI031834-07
Application #
2837415
Study Section
Special Emphasis Panel (ZAI1-PRJ-A (O2))
Program Officer
Miotti, Paolo G
Project Start
1992-03-01
Project End
2002-11-30
Budget Start
1998-12-01
Budget End
1999-11-30
Support Year
7
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Suny Downstate Medical Center
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
068552207
City
Brooklyn
State
NY
Country
United States
Zip Code
11203

  Publications

Ghosh, Mimi; Daniels, Jason; Pyra, Maria et al. (2018) Impact of chronic sexual abuse and depression on inflammation and wound healing in the female reproductive tract of HIV-uninfected and HIV-infected women. PLoS One 13:e0198412
Rice, Whitney S; Logie, Carmen H; Napoles, Tessa M et al. (2018) Perceptions of intersectional stigma among diverse women living with HIV in the United States. Soc Sci Med 208:9-17
Kelso-Chichetto, N E; Okafor, C N; Cook, R L et al. (2018) Association Between Depressive Symptom Patterns and Clinical Profiles Among Persons Living with HIV. AIDS Behav 22:1411-1422
Adams, Leah M; Wilson, Tracey E; Merenstein, Daniel et al. (2018) Using the Center for Epidemiologic Studies Depression Scale to assess depression in women with HIV and women at risk for HIV: Are somatic items invariant? Psychol Assess 30:97-105
Galárraga, Omar; Rana, Aadia; Rahman, Momotazur et al. (2018) The effect of unstable housing on HIV treatment biomarkers: An instrumental variables approach. Soc Sci Med 214:70-82
Enkhmaa, Byambaa; Anuurad, Erdembileg; Zhang, Wei et al. (2018) Effect of antiretroviral therapy on allele-associated Lp(a) level in women with HIV in the Women's Interagency HIV Study. J Lipid Res 59:1967-1976
Rubin, Leah H; Benning, Lorie; Keating, Sheila M et al. (2018) Variability in C-reactive protein is associated with cognitive impairment in women living with and without HIV: a longitudinal study. J Neurovirol 24:41-51
Belenky, Nadya; Pence, Brian W; Cole, Stephen R et al. (2018) Associations Between Medicare Part D and Out-of-Pocket Spending, HIV Viral Load, Adherence, and ADAP Use in Dual Eligibles With HIV. Med Care 56:47-53
Ascher, Simon B; Scherzer, Rebecca; Estrella, Michelle M et al. (2018) Association of Urinary Biomarkers of Kidney Injury with Estimated GFR Decline in HIV-Infected Individuals following Tenofovir Disoproxil Fumarate Initiation. Clin J Am Soc Nephrol 13:1321-1329
Hanna, David B; Moon, Jee-Young; Haberlen, Sabina A et al. (2018) Carotid artery atherosclerosis is associated with mortality in HIV-positive women and men. AIDS 32:2393-2403

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