Bronx Lebanon Hospital Center (BLHC) is a 565 bed voluntary hospital located in the South-Central Bronx which is affiliated with the Albert Einstein College of Medicine. BLHC is the primary health care provider to the approximately 453,000 people living in the South Bronx. The population served by the hospital is predominately black (48%) and Hispanic (47%). The neighborhood in which the hospital is located (zip codes 10456 and 10457) also has one of the highest rates of drug addiction and HIV seropositivity in the nation. The HIV seroprevalence rate in newborns in 1991 is reported to be 3.78%. The HIV team includes four full-time attending physicians, three full-time case managers (social workers), one clinical coordinator, a research RN, a pediatric nurse practitioner and two developmental psychologists. Five pediatric HIV clinic sessions are held weekly in children and their families receive comprehensive medical and social care coordinated by a social work case-manager. We are currently caring for 83 HIV infected children, 52 P-O infants and 52 seroreverters. The adult HIV program at BLHC is caring for over 1,300 patients. Pediatric referrals come from the adult clinic, foster care agencies, community health care facilities and the pediatric services at BLHC. The Pediatric HIV Team at BLHC is a participant in a CDC HIV Perinatal Transmission Study and other obstetrical programs designed to care for HIV- infected pregnant women. It is anticipated that our clinic population will exceed 300 by mid 1992. We were enrolled as a NICHD funded pediatric HIV clinical trial site in November, 1990. Twelve children have been enrolled in clinical studies. We are now applying to become a Pediatric ACTU.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01AI032914-04
Application #
2067829
Study Section
Acquired Immunodeficiency Syndrome Research Review Committee (AIDS)
Project Start
1992-03-01
Project End
1997-02-28
Budget Start
1995-03-01
Budget End
1996-02-29
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Bronx-Lebanon Hosp Center (Bronx, NY)
Department
Type
DUNS #
073258493
City
New York
State
NY
Country
United States
Zip Code
10456
McGowan, J P; Crane, M; Wiznia, A A et al. (1999) Combination antiretroviral therapy in human immunodeficiency virus-infected pregnant women. Obstet Gynecol 94:641-6
Pavlakis, S G; Lu, D; Frank, Y et al. (1998) Brain lactate and N-acetylaspartate in pediatric AIDS encephalopathy. AJNR Am J Neuroradiol 19:383-5
Wiznia, A A; Crane, M; Lambert, G et al. (1996) Zidovudine use to reduce perinatal HIV type 1 transmission in an urban medical center. JAMA 275:1504-6
Wiznia, A A; Lambert, G; Pavlakis, S (1996) Pediatric HIV infection. Med Clin North Am 80:1309-36
Pavlakis, S G; Frank, Y; Nocyze, M et al. (1994) Acquired immunodeficiency syndrome and the developing nervous system. Adv Pediatr 41:427-51