This is the renewal of the Women s and Infants Transmission Study at the University of Puerto Rico, Medical Sciences Campus. This application is for the fourth 5-year funding cycle. Accomplishments include the enrollment of the highest number of unique mother-infant pairs among the sites, the highest number of pregnant women and infants, the second highest number of deliveries, and a significant contribution of samples for the national or central WITS repository. Scientific accomplishments include the first comprehensive description of HIV disease progression in infants enrolled in the WITS; a consultative role in the CDC and PHS sponsored recommendations for the Prevention of Perinatal Transmission of HIV; CDC Disease Progression of Classification or staging for HIV infected infants; standardization and training of the neurological exam performed in WITS; and the reproductive choices of women enrolled in WITS. The WITS program in Puerto Rico has achieved a profound impact as a model program extended island wide for the prevention of perinatal transmission of HIV. Since September 1996 all infants born to women enrolled in the program have been free of HIV infection.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01AI034858-13
Application #
6906608
Study Section
Special Emphasis Panel (ZAI1-GLM-A (M2))
Program Officer
Rosario, Joana A
Project Start
1993-07-01
Project End
2006-05-31
Budget Start
2005-06-01
Budget End
2006-05-31
Support Year
13
Fiscal Year
2005
Total Cost
$884,566
Indirect Cost
Name
University of Puerto Rico Med Sciences
Department
Pediatrics
Type
Schools of Medicine
DUNS #
948108063
City
San Juan
State
PR
Country
United States
Zip Code
00936
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