Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project--Cooperative Agreements (U01)
Project #
3U01CA061498-02S1
Application #
2102235
Study Section
Special Emphasis Panel (SRC (59))
Project Start
1993-09-01
Project End
1996-08-31
Budget Start
1994-09-01
Budget End
1995-08-31
Support Year
2
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Cassaday, Ryan D; Sondel, Paul M; King, David M et al. (2007) A phase I study of immunization using particle-mediated epidermal delivery of genes for gp100 and GM-CSF into uninvolved skin of melanoma patients. Clin Cancer Res 13:540-9
Mahvi, D M; Shi, F-S; Yang, N-S et al. (2002) Immunization by particle-mediated transfer of the granulocyte-macrophage colony-stimulating factor gene into autologous tumor cells in melanoma or sarcoma patients: report of a phase I/IB study. Hum Gene Ther 13:1711-21
Rakhmilevich, A L; Imboden, M; Hao, Z et al. (2001) Effective particle-mediated vaccination against mouse melanoma by coadministration of plasmid DNA encoding Gp100 and granulocyte-macrophage colony-stimulating factor. Clin Cancer Res 7:952-61
Sondel, P M; Hank, J A (2001) Antibody-directed, effector cell-mediated tumor destruction. Hematol Oncol Clin North Am 15:703-21
Rakhmilevich, A L; Janssen, K; Hao, Z et al. (2000) Interleukin-12 gene therapy of a weakly immunogenic mouse mammary carcinoma results in reduction of spontaneous lung metastases via a T-cell-independent mechanism. Cancer Gene Ther 7:826-38
Hank, J A; Albertini, M R; Sondel, P M (1999) Monoclonal antibodies, cytokines and fusion proteins in the treatment of malignant disease. Cancer Chemother Biol Response Modif 18:210-22
Hank, J A; Surfus, J; Gan, J et al. (1999) Distinct clinical and laboratory activity of two recombinant interleukin-2 preparations. Clin Cancer Res 5:281-9
Surfus, J E; Hank, J A; Oosterwijk, E et al. (1996) Anti-renal-cell carcinoma chimeric antibody G250 facilitates antibody-dependent cellular cytotoxicity with in vitro and in vivo interleukin-2-activated effectors. J Immunother Emphasis Tumor Immunol 19:184-91
Helfand, S C; Hank, J A; Gan, J et al. (1996) Lysis of human tumor cell lines by canine complement plus monoclonal antiganglioside antibodies or natural canine xenoantibodies. Cell Immunol 167:99-107
Helfand, S C; Modiano, J F; Moore, P F et al. (1995) Functional interleukin-2 receptors are expressed on natural killer-like leukemic cells from a dog with cutaneous lymphoma. Blood 86:636-45

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