Abstract

2) The Genetics Core, led by Drs. Ring and Tyndale, will search for novel functional polymorphisms in nicotine kinetic and smoking behavior phenotype outliers, and characterize genotypes and haplotypes in clinical populations.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01DA020830-04
Application #
7647378
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
4
Fiscal Year
2008
Total Cost
$493,934
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Peng, Annie R; Schnoll, Robert; Hawk Jr, Larry W et al. (2018) Predicting smoking abstinence with biological and self-report measures of adherence to varenicline: Impact on pharmacogenetic trial outcomes. Drug Alcohol Depend 190:72-81
Taghavi, Taraneh; Novalen, Maria; Lerman, Caryn et al. (2018) A Comparison of Direct and Indirect Analytical Approaches to Measuring Total Nicotine Equivalents in Urine. Cancer Epidemiol Biomarkers Prev 27:882-891
Chenoweth, Meghan J; Ware, Jennifer J; Zhu, Andy Z X et al. (2018) Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences. Addiction 113:509-523
Tanner, Julie-Anne; Zhu, Andy Z; Claw, Katrina G et al. (2018) Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism. Pharmacogenet Genomics 28:7-16
Tanner, Julie-Anne; Prasad, Bhagwat; Claw, Katrina G et al. (2017) Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors. J Pharmacol Exp Ther 360:129-139
Goodman, Michelle S; Bridgman, Alanna C; Rabin, Rachel A et al. (2017) Differential effects of cannabis dependence on cortical inhibition in patients with schizophrenia and non-psychiatric controls. Brain Stimul 10:275-282
Schuit, Ewoud; Panagiotou, Orestis A; Munafò, Marcus R et al. (2017) Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers. Cochrane Database Syst Rev 9:CD011823
Chenoweth, Meghan J; Tyndale, Rachel F (2017) Pharmacogenetic Optimization of Smoking Cessation Treatment. Trends Pharmacol Sci 38:55-66
Barr, Mera S; Rajji, Tarek K; Zomorrodi, Reza et al. (2017) Impaired theta-gamma coupling during working memory performance in schizophrenia. Schizophr Res 189:104-110
Peng, Annie R; Morales, Mark; Wileyto, E Paul et al. (2017) Measures and predictors of varenicline adherence in the treatment of nicotine dependence. Addict Behav 75:122-129

Showing the most recent 10 out of 165 publications