The purpose of this grant application is to support Mayo Clinic membership in the Eastern Cooperative Oncology Group (ECOG). The goals are directed toward a greater understanding of cancer, a better understanding of cancer-related problems, development of improved cancer treatment programs, and improved cancer-patient survival. Mayo Clinic at its three campuses in Rochester, Minnesota, Jacksonville, Florida, and Scottsdale, Arizona, has the resources, personnel, facilities, and patient population to facilitate strong contributions to the research programs of ECOG. With the continued growth and development of the Mayo medical practice and continuing North Central Cancer Treatment Group (NCCTG) activities, we would anticipate significant protocol entry and scientific contribution. This ECOG affiliation and treatment programs which have evolved provide major benefits to Mayo Clinic, its investigators, regional cancer programs, and the large group of cancer patients who are involved in these research activities.
The specific aims of this grant proposal are to support the following aspects of Mayo Clinic ECOG research activities including: 1. Patient accrual to group-wide ECOG cancer treatment protocols 2. The evaluation of new protocol design and treatment regimens to provide background clinical data to justify group wide ECOG Phase II and III cancer treatment protocols 3. Coordination of and participation in adjunctive laboratory-based correlative studies in association with ECOG cancer treatment protocols 4. Participation in disease-specific activities and such administrative roles as might be appointed and appropriate.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA013650-26
Application #
2700305
Study Section
Cancer Clinical Investigation Review Committee (CCI)
Program Officer
Kaplan, Richard S
Project Start
1978-06-01
Project End
1999-04-30
Budget Start
1998-05-01
Budget End
1999-04-30
Support Year
26
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Gravis, Gwenaelle; Boher, Jean-Marie; Chen, Yu-Hui et al. (2018) Burden of Metastatic Castrate Naive Prostate Cancer Patients, to Identify Men More Likely to Benefit from Early Docetaxel: Further Analyses of CHAARTED and GETUG-AFU15 Studies. Eur Urol 73:847-855
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Roberts, Kathryn G; Gu, Zhaohui; Payne-Turner, Debbie et al. (2017) High Frequency and Poor Outcome of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Adults. J Clin Oncol 35:394-401
Haas, Naomi B; Manola, Judith; Uzzo, Robert G et al. (2016) Adjuvant sunitinib or sorafenib for high-risk, non-metastatic renal-cell carcinoma (ECOG-ACRIN E2805): a double-blind, placebo-controlled, randomised, phase 3 trial. Lancet 387:2008-16
Barta, Stefan K; Li, Hailun; Hochster, Howard S et al. (2016) Randomized phase 3 study in low-grade lymphoma comparing maintenance anti-CD20 antibody with observation after induction therapy: A trial of the ECOG-ACRIN Cancer Research Group (E1496). Cancer 122:2996-3004

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