Abstract

This community-based, clinical cancer research project provides community oncologists and primary care physicians and their patients the advantages of participation in clinical trials through affiliation with established national clinical research groups. This hospital-based program utilizes established cancer control activities to provide patients and physicians access to clinical protocols. The program will accrue at least ninety (90) patients annually to the selected protocols of the Southwest Oncology Group and the Radiation Therapy Oncology Group, under the management of a group of thirteen (13) participating physicians. The program allows for participation of these participating physician investigators in the internal activities of the two research bases, and utilizes a sophisticated data management system which will allow for sufficient data collection and analysis to furnish the National Cancer Institute with critical information regarding the diffusion of innovations in cancer care into community practice.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
2U10CA035200-04
Application #
3557627
Study Section
(SRC)
Project Start
1983-09-15
Project End
1990-05-31
Budget Start
1987-08-10
Budget End
1988-05-31
Support Year
4
Fiscal Year
1987
Total Cost
Indirect Cost

  Institution

Name
St. Vincent Medical Center
Department
Type
DUNS #
City
Los Angeles
State
CA
Country
United States
Zip Code
90057

  Publications

Tangen, Catherine M; Hussain, Maha H A; Higano, Celestia S et al. (2012) Improved overall survival trends of men with newly diagnosed M1 prostate cancer: a SWOG phase III trial experience (S8494, S8894 and S9346). J Urol 188:1164-9
Albain, Kathy S; Barlow, William E; Shak, Steven et al. (2010) Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial. Lancet Oncol 11:55-65
Albain, Kathy S; Barlow, William E; Ravdin, Peter M et al. (2009) Adjuvant chemotherapy and timing of tamoxifen in postmenopausal patients with endocrine-responsive, node-positive breast cancer: a phase 3, open-label, randomised controlled trial. Lancet 374:2055-63
Beer, Tomasz M; Tangen, Catherine M; Bland, Lisa B et al. (2006) The prognostic value of hemoglobin change after initiating androgen-deprivation therapy for newly diagnosed metastatic prostate cancer: A multivariate analysis of Southwest Oncology Group Study 8894. Cancer 107:489-96
Hutchins, Laura F; Green, Stephanie J; Ravdin, Peter M et al. (2005) Randomized, controlled trial of cyclophosphamide, methotrexate, and fluorouracil versus cyclophosphamide, doxorubicin, and fluorouracil with and without tamoxifen for high-risk, node-negative breast cancer: treatment results of Intergroup Protocol INT-010 J Clin Oncol 23:8313-21
Zalupski, Mark M; Rankin, Cathryn; Ryan, James R et al. (2004) Adjuvant therapy of osteosarcoma--A Phase II trial: Southwest Oncology Group study 9139. Cancer 100:818-25
Presant, C A; Wolf, W; Waluch, V et al. (2000) Enhancement of fluorouracil uptake in human colorectal and gastric cancers by interferon or by high-dose methotrexate: An in vivo human study using noninvasive (19)F-magnetic resonance spectroscopy. J Clin Oncol 18:255-61
Strickland, C J; Feigl, P; Upchurch, C et al. (1997) Improving breast self-examination compliance: a Southwest Oncology Group randomized trial of three interventions. Prev Med 26:320-32
Presant, C A; Wolf, W; Waluch, V et al. (1994) Association of intratumoral pharmacokinetics of fluorouracil with clinical response. Lancet 343:1184-7
Presant, C A; Wiseman, C; Blayney, D et al. (1990) Proposed criteria for serial evaluation of quality of life in cancer patients. J Natl Cancer Inst 82:322-3

Showing the most recent 10 out of 16 publications