Abstract

) Cedar Rapids Oncology Project CCOP, serves a six county region of eastern Iowa and three counties of western Illinois with a total population base of over 400,000 individuals. At least 1600 new cancer cases will be seen annually by CCOP investigators and institutions. Components include St. Luke's Hospital and Mercy Medical Center in Cedar Rapids, Iowa, and Trinity Medical Center in Moline, Illinois. Comprehensive cancer care services are available and a multidisciplinary team of physicians, nurses, and research associates has been developed. The CCOP uses NCCTG as its primary research base, with its studies supplemented by ECOG and NSABP. Eight years of continuous CCOP participation has refined its operational strategies and data management procedures. It is a highly efficient organization, recognized for quality, by its research bases, and by external auditors. Strong participation has been accomplished in the areas of breast, colorectal, lung and brain cancer. A comprehensive cancer prevention and control program has been established. Efforts will continue for greater recruitment of minority participants. The Cedar Rapids Oncology Project CCOP requests continued support in providing community based cancer research to its communities.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA052352-13
Application #
6512678
Study Section
Special Emphasis Panel (ZCA1-RLB-7 (J3))
Program Officer
Kelaghan, Joseph
Project Start
1990-09-15
Project End
2003-05-31
Budget Start
2002-06-01
Budget End
2003-05-31
Support Year
13
Fiscal Year
2002
Total Cost
$580,846
Indirect Cost

  Institution

Name
Cedar Rapids Oncology Project
Department
Type
DUNS #
186618497
City
Cedar Rapids
State
IA
Country
United States
Zip Code
52403

  Publications

Barton, Debra L; Sloan, Jeff A; Shuster, Lynne T et al. (2018) Evaluating the efficacy of vaginal dehydroepiandosterone for vaginal symptoms in postmenopausal cancer survivors: NCCTG N10C1 (Alliance). Support Care Cancer 26:643-650
Sio, Terence T; Atherton, Pamela J; Birckhead, Brandon J et al. (2016) Repeated measures analyses of dermatitis symptom evolution in breast cancer patients receiving radiotherapy in a phase 3 randomized trial of mometasone furoate vs placebo (N06C4 [alliance]). Support Care Cancer 24:3847-55
Pachman, Deirdre R; Qin, Rui; Seisler, Drew et al. (2016) Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505). Support Care Cancer 24:5059-5068
Van Loon, Katherine; Espinoza, Anne M; Fogelman, David R et al. (2014) Should combination chemotherapy serve as the backbone in clinical trials of advanced pancreatic cancer? A pooled analysis of phase II trials of gemcitabine-containing doublets plus bevacizumab. Pancreas 43:343-9
Leal, Alexis D; Qin, Rui; Atherton, Pamela J et al. (2014) North Central Cancer Treatment Group/Alliance trial N08CA-the use of glutathione for prevention of paclitaxel/carboplatin-induced peripheral neuropathy: a phase 3 randomized, double-blind, placebo-controlled study. Cancer 120:1890-7
Province, M A; Goetz, M P; Brauch, H et al. (2014) CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations. Clin Pharmacol Ther 95:216-27
Galanis, Evanthia; Anderson, S Keith; Lafky, Jackie M et al. (2013) Phase II study of bevacizumab in combination with sorafenib in recurrent glioblastoma (N0776): a north central cancer treatment group trial. Clin Cancer Res 19:4816-23
Brown, Lindsay C; Atherton, Pamela J; Neben-Wittich, Michelle A et al. (2013) Assessment of long-term rectal function in patients who received pelvic radiotherapy: a pooled North Central Cancer Treatment Group trial analysis, N09C1. Support Care Cancer 21:2869-77
Kottschade, Lisa A; Suman, Vera J; Perez, Domingo G et al. (2013) A randomized phase 2 study of temozolomide and bevacizumab or nab-paclitaxel, carboplatin, and bevacizumab in patients with unresectable stage IV melanoma : a North Central Cancer Treatment Group study, N0775. Cancer 119:586-92
Lavoie Smith, Ellen M; Barton, Debra L; Qin, Rui et al. (2013) Assessing patient-reported peripheral neuropathy: the reliability and validity of the European Organization for Research and Treatment of Cancer QLQ-CIPN20 Questionnaire. Qual Life Res 22:2787-99

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