Abstract

The H. Lee Moffitt Cancer Center and Research Institute seeks to establish a CCOP Research Base for cancer prevention and control studies. Seven protocols are submitted with this application as potential studies to be implemented. Signed letters of agreement from NCI funded CCOPs have projected over 200 patient registrations per year on these studies. The application is proposed from a team of investigators who have more than 10 years experience in a CCOP Research Base (as PI), in multi-institutional cancer control and clinical trials and in cancer prevention and control research. The Cancer Center proposes a data management and quality control system that meets Federal regulatory requirements and is presently used in another large, NIH funded multi- institutional prevention trial. The Research Base will comply with DCP/NCI requirements regarding protocol review and monitoring and the terms of the cooperative agreement. We make a commitment to the recruitment of women and minorities and will seek CCOP affiliates to help us meet this goal. The combination of a strong scientific portfolio, the expertise and experience in the development and implementation of cancer prevention and control protocols in a multi-institutional setting and the strong indication of support from DCP/NCI funded CCOPs encourages us to believe that we can be successful in meeting our goals.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
1U10CA081920-01A1
Application #
6144455
Study Section
Special Emphasis Panel (ZCA1-SRRB-7 (J1))
Project Start
2000-06-01
Project End
2003-05-31
Budget Start
2000-06-01
Budget End
2001-05-31
Support Year
1
Fiscal Year
2000
Total Cost
$575,473
Indirect Cost

  Institution

Name
University of South Florida
Department
Pediatrics
Type
Schools of Medicine
DUNS #
City
Tampa
State
FL
Country
United States
Zip Code
33612

  Publications

Guglin, Maya; Munster, Pamela; Fink, Angelina et al. (2017) Lisinopril or Coreg CR in reducing cardiotoxicity in women with breast cancer receiving trastuzumab: A rationale and design of a randomized clinical trial. Am Heart J 188:87-92
Minasian, Lori M; Tangen, Catherine M; Wickerham, D Lawrence (2015) Ongoing Use of Data and Specimens From National Cancer Institute-Sponsored Cancer Prevention Clinical Trials in the Community Clinical Oncology Program. Semin Oncol 42:748-63
Bradfield, Scott M; Sandler, Eric; Geller, Thomas et al. (2015) Glutamic acid not beneficial for the prevention of vincristine neurotoxicity in children with cancer. Pediatr Blood Cancer 62:1004-10
Couluris, Marisa; Kinder, Brent W; Xu, Ping et al. (2012) Treatment of idiopathic pulmonary fibrosis with losartan: a pilot project. Lung 190:523-7
Munster, Pamela N; Moore, Amy P; Ismail-Khan, Roohi et al. (2012) Randomized trial using gonadotropin-releasing hormone agonist triptorelin for the preservation of ovarian function during (neo)adjuvant chemotherapy for breast cancer. J Clin Oncol 30:533-8
Aguado Loi, Claudia X; Taylor, Teletia R; McMillan, Susan et al. (2012) Use and helpfulness of self-administered stress management therapy in patients undergoing cancer chemotherapy in community clinical settings. J Psychosoc Oncol 30:57-80
Couluris, Marisa; Schnapf, Bruce M; Casey, Allyson et al. (2011) How to measure secondhand smoke exposure in a pediatric clinic setting. Arch Pediatr Adolesc Med 165:670-1
Kumar, Nagi B; Kang, Loveleen; Pow-Sang, Julio et al. (2010) Results of a randomized phase I dose-finding trial of several doses of isoflavones in men with localized prostate cancer: administration prior to radical prostatectomy. J Soc Integr Oncol 8:3-13
Kumar, Nagi B; Besterman-Dahan, Karen; Kang, Loveleen et al. (2008) Results of a Randomized Clinical Trial of the Action of Several Doses of Lycopene in Localized Prostate Cancer: Administration Prior to Radical Prostatectomy. Clin Med Urol 1:1-14
Gross-King, Margaret; Booth-Jones, Margaret; Couluris, Marisa (2008) Neurocognitive impairment in children treated for cancer: how do we measure cognitive outcomes? J Pediatr Oncol Nurs 25:227-32

Showing the most recent 10 out of 15 publications