We present qualifications in this application to justify continued participation in the Neonatal Network. They are as follow: Size: Few, if any single, nurseries can contribute a larger patient population for study. Expertise: We have an uncommonly rich and protracted experience in multicenter trials. Our scientific research and its publications are substantial; the diversity and depth of expert support personnel is noteworthy. Training program: As a division of the Department of pediatrics, Newborn Medicine is taught in accordance with residency requirements. We are approved for fellowship training in Neonatal- perinatal Medicine. Administrative control: This large unit has been favored with considerable intramural control and institutional priority by virtue of its role in community health and its research activities. Facilities: Copious space, ample equipment and intramural control of a clinical laboratory with broad functions provide the wherewithal for effective clinical investigation. Perinatal data system: We have compiled data manually since 1972, by computer since 1979. We have extensive data stored for the past 15 years, describing demographics, diagnoses, outcomes, procedures and therapies. Inborn admissions: Approximately 95% of admissions are inborn and the number of back-transferred outborn infants is negligible, thereby increasing the number of babies available for study. Obstetrical coordination: The Neonatal Division is an official component of the Department of Obstetrics and Gynecology. Historically, our relationship with the obstetricians has been exemplary and productive. Fiscal efficiency: We are adept at budget management; in previous multicenter studies our costs have been lower than most other participants.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10HD021415-15
Application #
6181506
Study Section
Special Emphasis Panel (SRC (NN))
Program Officer
Spong, Catherine
Project Start
1991-04-01
Project End
2003-03-31
Budget Start
2000-04-01
Budget End
2003-03-31
Support Year
15
Fiscal Year
2000
Total Cost
$1,154,938
Indirect Cost
Name
University of Tennessee Health Science Center
Department
Pediatrics
Type
Schools of Medicine
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163
Ambalavanan, Namasivayam; Cotten, C Michael; Page, Grier P et al. (2015) Integrated genomic analyses in bronchopulmonary dysplasia. J Pediatr 166:531-7.e13
Ment, Laura R; Ådén, Ulrika; Bauer, Charles R et al. (2015) Genes and environment in neonatal intraventricular hemorrhage. Semin Perinatol 39:592-603
Adams-Chapman, Ira; Bann, Carla; Carter, Sheena L et al. (2015) Language outcomes among ELBW infants in early childhood. Early Hum Dev 91:373-9
Stoll, Barbara J; Hansen, Nellie I; Bell, Edward F et al. (2015) Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012. JAMA 314:1039-51
Patel, Ravi M; Kandefer, Sarah; Walsh, Michele C et al. (2015) Causes and timing of death in extremely premature infants from 2000 through 2011. N Engl J Med 372:331-40
Wadhawan, R; Oh, W; Hintz, S R et al. (2014) Neurodevelopmental outcomes of extremely low birth weight infants with spontaneous intestinal perforation or surgical necrotizing enterocolitis. J Perinatol 34:64-70
Morriss Jr, Frank H; Saha, Shampa; Bell, Edward F et al. (2014) Surgery and neurodevelopmental outcome of very low-birth-weight infants. JAMA Pediatr 168:746-54
Maheshwari, Akhil; Schelonka, Robert L; Dimmitt, Reed A et al. (2014) Cytokines associated with necrotizing enterocolitis in extremely-low-birth-weight infants. Pediatr Res 76:100-8
Hartnett, M Elizabeth; Morrison, Margaux A; Smith, Silvia et al. (2014) Genetic variants associated with severe retinopathy of prematurity in extremely low birth weight infants. Invest Ophthalmol Vis Sci 55:6194-203
Kelleher, John; Salas, Ariel A; Bhat, Ramachandra et al. (2014) Prophylactic indomethacin and intestinal perforation in extremely low birth weight infants. Pediatrics 134:e1369-77

Showing the most recent 10 out of 102 publications