Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI051973-02
Application #
6616877
Study Section
Special Emphasis Panel (ZAI1)
Project Start
2002-08-01
Project End
2003-05-31
Budget Start
Budget End
Support Year
2
Fiscal Year
2002
Total Cost
Indirect Cost
Name
La Jolla Institute
Department
Type
DUNS #
603880287
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Solomon, Michelle; Balasa, Balaji; Sarvetnick, Nora (2010) CCR2 and CCR5 chemokine receptors differentially influence the development of autoimmune diabetes in the NOD mouse. Autoimmunity 43:156-63
Bresson, Damien; Fradkin, Matthew; Manenkova, Yulia et al. (2010) Genetic-induced variations in the GAD65 T-cell repertoire governs efficacy of anti-CD3/GAD65 combination therapy in new-onset type 1 diabetes. Mol Ther 18:307-16
Bresson, Damien; von Herrath, Matthias (2008) Resuscitating adaptive Tregs with combination therapies? Novartis Found Symp 292:50-60;discussion 60-7, 122-9, 2
Filippi, Christophe M; Juedes, Amy E; Oldham, Janine E et al. (2008) Transforming growth factor-beta suppresses the activation of CD8+ T-cells when naive but promotes their survival and function once antigen experienced: a two-faced impact on autoimmunity. Diabetes 57:2684-92
Yadav, Deepak; Fine, Cody; Azuma, Miyuki et al. (2007) B7-1 mediated costimulation regulates pancreatic autoimmunity. Mol Immunol 44:2616-24
Bresson, D; von Herrath, M (2007) Moving towards efficient therapies in type 1 diabetes: to combine or not to combine? Autoimmun Rev 6:315-22
Martinic, Marianne M; Juedes, Amy E; Bresson, Damien et al. (2007) Minimal impact of a de novo-expressed beta-cell autoantigen on spontaneous diabetes development in NOD mice. Diabetes 56:1059-68
Yadav, Deepak; Sarvetnick, Nora (2007) Immunomodulation of the anti-islet CD8 T cell response by B7-2. J Clin Immunol 27:221-6
Fousteri, Georgia; von Herrath, Matthias; Bresson, Damien (2007) Mucosal exposure to antigen: cause or cure of type 1 diabetes? Curr Diab Rep 7:91-8
Burrer, Renaud; Buchmeier, Michael J; Wolfe, Tom et al. (2007) Exacerbated pathology of viral encephalitis in mice with central nervous system-specific autoantibodies. Am J Pathol 170:557-66

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